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EPH Receptor B4 Products

(EPH Receptor B4 (EPHB4))
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008].

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Featured EPH Receptor B4 Categories

EPH Receptor B4 Antibodies

High quality antibodies with extensive validation data.

EPH Receptor B4 ELISA Kits

Reliable ELISA kits for a wide range of species.

EPH Receptor B4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EPH Receptor B4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, FACS
Validations
  • (5)
Cat. No. ABIN7043127
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
  • (2)
Cat. No. ABIN969107
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7151868
Quantity 100 μL
Datasheet Datasheet

Recommended EPH Receptor B4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966541
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882757
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886077
Quantity 96 tests
Datasheet Datasheet

Recommended EPH Receptor B4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274546
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352945
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN6387866
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EPH Receptor B4 products

Neal, Nornes, Payne, Wallace, Fritzsche, Louphrasitthiphol, Wilkinson, Chouliaras, Liu, Plant, Sholapurkar, Ratnayaka, Herzog, Bond, Chico, Bou-Gharios, De Val: "Venous identity requires BMP signalling through ALK3." in: Nature communications, Vol. 10, Issue 1, pp. 453, (2019) (PubMed).

Payne, Gunadasa-Rohling, Neal, Redpath, Patel, Chouliaras, Ratnayaka, Smart, De Val: "Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart." in: Nature communications, Vol. 10, Issue 1, pp. 3276, (2019) (PubMed).

Grandi, Zini, Palese, Giorgio, Tognolini, Marchesani, Bruno, Flammini, Cantoni, Castelli, Lodola, Fusari, Barocelli, Bertoni: "Targeting the Eph/Ephrin System as Anti-Inflammatory Strategy in IBD." in: Frontiers in pharmacology, Vol. 10, pp. 691, (2019) (PubMed).

Toray, Hasegawa, Sakagami, Tsuchiya, Kudo, Zhao, Moritani, Abe, Yoshida, Yamamoto, Yamamoto, Oda, Udagawa, Luiz de Freitas, Li: "Histochemical assessment for osteoblastic activity coupled with dysfunctional osteoclasts in c-src deficient mice." in: Biomedical research (Tokyo, Japan), Vol. 38, Issue 2, pp. 123-134, (2018) (PubMed).

Wang, Collins, Foster, Bai, Hashimoto, Santana, Shu, Dardik: "Eph-B4 mediates vein graft adaptation by regulation of endothelial nitric oxide synthase." in: Journal of vascular surgery, Vol. 65, Issue 1, pp. 179-189, (2017) (PubMed).

Martin-Almedina, Martinez-Corral, Holdhus, Vicente, Fotiou, Lin, Petersen, Simpson, Hoischen, Gilissen, Jeffery, Atton, Karapouliou, Brice, Gordon, Wiseman, Wedin, Rockson, Jeffery, Mortimer, Snyder et al.: "EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. ..." in: The Journal of clinical investigation, Vol. 126, Issue 8, pp. 3080-8, (2016) (PubMed).

Fuggetta, Bordignon, Cottarelli, Macchi, Frezza, Cordiali-Fei, Ensoli, Ciafrè, Marino-Merlo, Mastino, Ravagnan: "Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 118, (2016) (PubMed).

Depner, Zum Buttel, Böğürcü, Cuesta, Aburto, Seidel, Finkelmeier, Foss, Hofmann, Kaulich, Barbus, Segarra, Reifenberger, Garvalov, Acker, Acker-Palmer: "EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance." in: Nature communications, Vol. 7, pp. 12329, (2016) (PubMed).

Zhang, Brady, Liang, Wu, Henkemeyer, Yan: "EphB4 forward signalling regulates lymphatic valve development." in: Nature communications, Vol. 6, pp. 6625, (2016) (PubMed).

Becerikli, Merwart, Lam, Suppelna, Rittig, Mirmohammedsadegh, Stricker, Theiss, Singer, Jacobsen, Steinstraesser: "EPHB4 tyrosine-kinase receptor expression and biological significance in soft tissue sarcoma." in: International journal of cancer. Journal international du cancer, Vol. 136, Issue 8, pp. 1781-91, (2015) (PubMed).

Synonyms and alternative names related to EPH Receptor B4

EPH receptor B4 (EPHB4), EPH receptor B4 L homeolog (ephb4.L), EPH receptor B4 S homeolog (ephb4.S), EPH receptor B4 (ephb4), Eph receptor B4 (Ephb4), EPH receptor B4 (Ephb4), eph receptor B4a (ephb4a), eph receptor B4b (ephb4b), AI042935, cb417, cb646, EphB-rtk8, ephB4, ephB4a, ephb4b, HTK, htk, Htk, MDK2, MGC130997, MYK1, myk1, Myk1, rtk5, rtk8, TYRO11, tyro11, Tyro11

Protein level used designations for EPH Receptor B4

  • ephrin receptor EphB4
  • ephrin type-B receptor 4
  • hepatoma transmembrane kinase
  • soluble EPHB4 variant 1
  • soluble EPHB4 variant 2
  • soluble EPHB4 variant 3
  • tyrosine-protein kinase TYRO11
  • tyrosine-protein kinase receptor HTK
  • EPH receptor B4
  • eph receptor tyrosine kinase
  • ephrin type-B receptor 4-like
  • developmental kinase 2
  • mDK-2
  • tyrosine kinase MYK-1
  • eph receptor B4a
  • eph-like receptor tyrosine kinase 5
  • ephrin type-B receptor 4 pseudogene
  • eph receptor B4b
  • eph-like receptor tyrosine kinase 8
  • unp164
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