EPAS1 Products
(Endothelial PAS Domain Protein 1 (EPAS1))
Categories
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009].
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Featured EPAS1 Categories
EPAS1 Antibodies
High quality antibodies with extensive validation data.
EPAS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
EPAS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EPAS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7435523
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7435526
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (6)
Cat. No.
ABIN3187839
Quantity
100 μL
Datasheet
Datasheet
Recommended EPAS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955560
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955561
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962916
Quantity
96 tests
Datasheet
Datasheet
Recommended EPAS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1352871
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352872
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7420924
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our EPAS1 products
: "Hypoxia-inducible factors in arteriovenous fistula maturation: A prospective cohort study." in: European journal of clinical investigation, Vol. 50, Issue 12, pp. e13350, (2020) (PubMed).: "Selective tubular activation of hypoxia-inducible factor-2α has dual effects on renal fibrosis." in: Scientific reports, Vol. 7, Issue 1, pp. 11351, (2019) (PubMed).
: "Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism." in: Molecular cancer therapeutics, Vol. 17, Issue 8, pp. 1781-1792, (2019) (PubMed).
: "HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia." in: Cellular and molecular life sciences : CMLS, Vol. 76, Issue 4, pp. 809-825, (2019) (PubMed).
: "Deletion of an intronic HIF-2α binding site suppresses hypoxia-induced WT1 expression." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1862, Issue 1, pp. 71-83, (2019) (PubMed).
: "TRIB3 Promotes the Proliferation and Invasion of Renal Cell Carcinoma Cells via Activating MAPK Signaling Pathway." in: International journal of biological sciences, Vol. 15, Issue 3, pp. 587-597, (2019) (PubMed).
: "Hypoxia Restrains Lipid Utilization via Protein Kinase A and Adipose Triglyceride Lipase Downregulation through Hypoxia-Inducible Factor." in: Molecular and cellular biology, Vol. 39, Issue 2, (2019) (PubMed).
: "Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer." in: eLife, Vol. 7, (2019) (PubMed).
: "Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload." in: The Journal of clinical investigation, Vol. 129, Issue 1, pp. 336-348, (2019) (PubMed).
: "Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression." in: The Journal of clinical investigation, Vol. 129, Issue 2, pp. 631-646, (2019) (PubMed).
Synonyms and alternative names related to EPAS1
endothelial PAS domain protein 1 (EPAS1), endothelial PAS domain protein 1 (epas1), endothelial PAS domain protein 1 (Epas1), endothelial PAS domain protein 1 L homeolog (epas1.L), bHLHe73, bhlhe73, ECYT4, ecyt4, EPAS, EPAS-1, EPAS1, HIF-2alpha, hif2, HIF2A, Hif2a, hif2a, hif2alpha, HLF, hlf, HRF, MOP2, mop2, PASD2, pasd2Protein level used designations for EPAS1
- endothelial PAS domain protein 1
- endothelial PAS domain-containing protein 1-like
- EPAS-1
- HIF-1-alpha-like factor
- HIF-1alpha-like factor
- HIF-2-alpha
- HIF2-alpha
- PAS domain-containing protein 2
- basic-helix-loop-helix-PAS protein MOP2
- class E basic helix-loop-helix protein 73
- endothelial PAS domain-containing protein 1
- hypoxia-inducible factor 2 alpha
- hypoxia-inducible factor 2-alpha
- member of PAS protein 2
- HIF-related factor
- HIF1 alpha-like factor
- HIF1alpha-like factor
- HLF (HIF1alpha-like factor)
- Hif like protein
- hypoxia inducible transcription factor 2alpha
- mHLF
- HIF-2 alpha
- HIF2 alpha
- hypoxia inducible factor 2, alpha subunit
- hypoxia inducible factor 2a
- HIF-2alpha
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