ENPP2 Products
(Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
Categories
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008].
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Featured ENPP2 Categories
ENPP2 Antibodies
High quality antibodies with extensive validation data.
ENPP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ENPP2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ENPP2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, ICC, IF
Validations
- (1)
- (6)
Cat. No.
ABIN2856278
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (5)
Cat. No.
ABIN650746
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7427858
Quantity
100 μL
Datasheet
Datasheet
Recommended ENPP2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955502
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955503
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955504
Quantity
96 tests
Datasheet
Datasheet
Recommended ENPP2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274534
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274543
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
- (1)
Cat. No.
ABIN7538220
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ENPP2 products
: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." in: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).: "NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment." in: Cellular and molecular life sciences : CMLS, (2020) (PubMed).
: "Polyoxometalates--potent and selective ecto-nucleotidase inhibitors." in: Biochemical pharmacology, Vol. 93, Issue 2, pp. 171-81, (2015) (PubMed).
: "The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 133-42, (2006) (PubMed).
: "NPP-type ectophosphodiesterases: unity in diversity." in: Trends in biochemical sciences, Vol. 30, Issue 10, pp. 542-50, (2005) (PubMed).
: "Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources." in: Journal of neurochemistry, Vol. 92, Issue 4, pp. 904-14, (2005) (PubMed).
: "Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma." in: FEBS letters, Vol. 571, Issue 1-3, pp. 197-204, (2004) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyms and alternative names related to ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (Enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog (enpp2.L), ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog (enpp2.S), ATX, atx, ATX-X, AUTOTAXIN, autotaxin, enpp2, enpp2a, enpp2b, LysoPLD, MGC132047, NPP2, Npps2, PD-IALPHA, PD-Ialpha, PDNP2, Pdnp2, zgc:63550Protein level used designations for ENPP2
- E-NPP 2
- autotaxin-t
- ectonucleotide pyrophosphatase/phosphodiesterase family member 2
- extracellular lysophospholipase D
- phosphodiesterase I/nucleotide pyrophosphatase 2
- plasma lysophospholipase D
- autotaxin
- lysoPLD
- phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin)
- ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)
- ectonucleotide pyrophosphatase/phosphodiesterase 2
- ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2 preproprotein
- ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog
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