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Endoribonuclease Dcr-1 Antibodies

(Endoribonuclease Dcr-1 (Dcr-1))
Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing.

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Featured Endoribonuclease Dcr-1 Categories

Endoribonuclease Dcr-1 Antibodies

High quality antibodies with extensive validation data.

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Latest Publications for our Endoribonuclease Dcr-1 products

Duchaine, Wohlschlegel, Kennedy, Bei, Conte, Pang, Brownell, Harding, Mitani, Ruvkun, Yates, Mello: "Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways." in: Cell, Vol. 124, Issue 2, pp. 343-54, (2006) (PubMed).

Denli, Tops, Plasterk, Ketting, Hannon: "Processing of primary microRNAs by the Microprocessor complex." in: Nature, Vol. 432, Issue 7014, pp. 231-5, (2004) (PubMed).

Tabara, Yigit, Siomi, Mello: "The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans." in: Cell, Vol. 109, Issue 7, pp. 861-71, (2002) (PubMed).

Synonyms and alternative names related to Endoribonuclease Dcr-1

Endoribonuclease dcr-1 (dcr-1)
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