ELF3 Products
(E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))
Categories
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
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Featured ELF3 Categories
ELF3 Antibodies
High quality antibodies with extensive validation data.
ELF3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ELF3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN6140125
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN6140124
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN515249
Quantity
100 μg
Datasheet
Datasheet
Recommended ELF3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5690871
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385553
Quantity
96 tests
Datasheet
Datasheet
Recommended ELF3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352684
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352682
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092444
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ELF3 products
: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).: "Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells." in: Frontiers in physiology, Vol. 10, pp. 1308, (2019) (PubMed).
: "A transcriptional repressive role for epithelial-specific ETS factor ELF3 on oestrogen receptor alpha in breast cancer cells." in: The Biochemical journal, Vol. 473, Issue 8, pp. 1047-61, (2016) (PubMed).
: "In vitro cultured primary cells from a human utricle explant possesses hair cell like characteristics." in: Journal of molecular histology, Vol. 42, Issue 4, pp. 365-70, (2011) (PubMed).
: "Advancing towards a tissue-engineered tympanic membrane: silk fibroin as a substratum for growing human eardrum keratinocytes." in: Journal of biomaterials applications, Vol. 24, Issue 7, pp. 591-606, (2010) (PubMed).
: "A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking." in: Analytical biochemistry, Vol. 383, Issue 2, pp. 265-9, (2008) (PubMed).
: "Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38941-50, (2006) (PubMed).
: "Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family." in: Molecular and cellular biology, Vol. 17, Issue 8, pp. 4419-33, (1997) (PubMed).
Synonyms and alternative names related to ELF3
E74 like ETS transcription factor 3 (elf3), E74-like factor 3 (Elf3), E74 like ETS transcription factor 3 (Elf3), E74 like ETS transcription factor 3 (ELF3), epr-1, EPR-1, ert, ERT, ese-1, ESE-1, esx, ESX, jenProtein level used designations for ELF3
- E74-like factor 3 (ets domain transcription factor, epithelial-specific)
- ETS-related transcription factor Elf-3
- epithelial-restricted with serine box
- epithelium-restricted Ets protein ESX
- epithelium-specific Ets transcription factor 1
- E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific)
- E74-like factor 3 (ets domain transcription factor)
- ets domain transcription factor, serine box (epithelial-specific)
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