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ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Products

(ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))

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The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012].

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Featured ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Categories

ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Antibodies

High quality antibodies with extensive validation data.

ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Antibodies

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Validations
Cat. No.
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Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
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Cat. No. ABIN652911
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
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Cat. No. ABIN560725
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
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Cat. No. ABIN7266913
Quantity 100 μL
Datasheet Datasheet

Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) ELISA Kits

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Reactivity
Analytical Method
Validations
Cat. No.
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Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6966469
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
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Cat. No. ABIN6955527
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6955528
Quantity 96 tests
Datasheet Datasheet

Recommended ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) Proteins

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Reactivity Human
Source Wheat germ
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Cat. No. ABIN7477790
Quantity 2 μg
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1352665
Quantity 10 μg
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Reactivity Human
Source HEK-293 Cells
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Cat. No. ABIN2720123
Quantity 20 μg
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Latest Publications for our ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) products

Ni, Zhou, Song, Chen, Wang, Du, Zhang: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." in: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).

Gorbatenko, Olesen, Loebl, Sigurdsson, Bianchi, Pedraz-Cuesta, Christiansen, Pedersen: "Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes." in: The Biochemical journal, Vol. 473, Issue 21, pp. 4027-4044, (2016) (PubMed).

Sung, Chu, Chen, Liao, Lee: "Positive regulation of HIF-1A expression by EBV oncoprotein LMP1 in nasopharyngeal carcinoma cells." in: Cancer letters, Vol. 382, Issue 1, pp. 21-31, (2016) (PubMed).

Li, Lu, Dai, Torregroza, Hla, Evans: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." in: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).

Chang, Lu, Li, Hsieh, Xiong, Ghosh, Evans, Elemento, Hla: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).

Choudhury, de Lima Alves, de Andrés-Aguayo, Graf, Cáceres, Rappsilber, Michlewski: "Tissue-specific control of brain-enriched miR-7 biogenesis." in: Genes & development, Vol. 27, Issue 1, pp. 24-38, (2013) (PubMed).

Chu, Kulp, Chen: "Insulin-like growth factor-I receptor is suppressed through transcriptional repression and mRNA destabilization by a novel energy restriction-mimetic agent." in: Carcinogenesis, Vol. 34, Issue 12, pp. 2694-705, (2013) (PubMed).

Kani, Faca, Hughes, Zhang, Fang, Shahbaba, Luethy, Erde, Schmidt, Pitteri, Zhang, Katz, Gross, Plevritis, McIntosh, Jain, Hanash, Agus, Mallick: "Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition." in: Molecular cancer therapeutics, Vol. 11, Issue 5, pp. 1071-81, (2012) (PubMed).

Chu, Chuang, Kulp, Chen: "The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition." in: The Journal of biological chemistry, Vol. 287, Issue 52, pp. 43639-50, (2012) (PubMed).

García-Domínguez, Morello, Cisneros, Kontoyiannis, Frade: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." in: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).

Synonyms and alternative names related to ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R)

ELAV like RNA binding protein 1 (ELAVL1), ELAV like RNA binding protein 1 (Elavl1), ELAV-like protein 1 (elav1), ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) (Elavl1), ELAV like RNA binding protein 1a (elavl1a), ELAV like RNA binding protein 1 L homeolog (elavl1.L), ELAV like RNA binding protein 1 S homeolog (elavl1.S), 2410055N02Rik, ELAV1, elav1, Elavl1, elavl1, elavl1-a, elavl1-b, elra, elrA, ElrA, fa25f08, fb59a02, fc60g02, Hua, hua, HUR, HuR, hur, MelG, melg, p36, W91709, wu:fa25f08, wu:fb59a02, wu:fc60g02, Xel-1, zHuA

Protein level used designations for ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R)

  • ELAV-like protein 1
  • Hu antigen R
  • embryonic lethal, abnormal vision, drosophila, homolog-like 1
  • hu-antigen R
  • ELAV-like 1 (Hu antigen R)
  • ELAV like 1
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • HU-antigen A
  • elav-like generic protein
  • melG
  • elav-related A
  • embryonic lethal, abnormal vision-related A
  • etID309757.2
  • 36 kDa eCPE-binding protein
  • 36 kDa eCPEB
  • 36 kDa embryonic-type cytoplasmic polyadenylation element-binding protein
  • 36-kDa eCPE-binding protein
  • 36-kDa eCPEB
  • 36-kDa embryonic-type cytoplasmic polyadenylation element (CPE)-binding protein
  • ELAV-like protein 1-A
  • Protein ElrA-A
  • ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
  • ELAV-like protein 1-B
  • Protein ElrA-B
  • elrA
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