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EIF5A2 Products

(Eukaryotic Translation Initiation Factor 5A2 (EIF5A2))

Categories

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

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Featured EIF5A2 Categories

EIF5A2 Antibodies

High quality antibodies with extensive validation data.

EIF5A2 ELISA Kits

Reliable ELISA kits for a wide range of species.

EIF5A2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF5A2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), IF, FACS
Validations
  • (5)
Cat. No. ABIN1497996
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7073893
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN566034
Quantity 100 μg
Datasheet Datasheet

Recommended EIF5A2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966612
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955667
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951365
Quantity 96 tests
Datasheet Datasheet

Recommended EIF5A2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352634
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352632
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692565
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our EIF5A2 products

Fujimura, Wright, Strnadel, Kaushal, Metildi, Lowy, Bouvet, Kelber, Klemke: "A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer." in: Cancer research, Vol. 74, Issue 22, pp. 6671-81, (2014) (PubMed).

Murata, Minami, Iwakawa, Yokota, Usui, Tsuta, Shiraishi, Sakashita, Satomi, Iijima, Noguchi: "ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma." in: Cancer science, Vol. 105, Issue 4, pp. 490-7, (2014) (PubMed).

Luo, Hua, Rao, Liao, Kung, Zeng, Guan, Chen, Xie: "Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder." in: Cancer science, Vol. 100, Issue 5, pp. 896-902, (2009) (PubMed).

Chen, Luo, Hua, Zhou, Lin, Kung, Zeng, Guan, Xie: "Overexpression of EIF-5A2 is an independent predictor of outcome in patients of urothelial carcinoma of the bladder treated with radical cystectomy." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 2, pp. 400-8, (2009) (PubMed).

Yang, Xie, Liu, Luo, Li, Hua, Wu, Kung, Zeng, Guan: "Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma." in: Gynecologic oncology, Vol. 112, Issue 2, pp. 314-8, (2009) (PubMed).

Xie, Ma, Pan, Wu, Liu, Wu, Kung, Guan: "Overexpression of EIF-5A2 is associated with metastasis of human colorectal carcinoma." in: Human pathology, Vol. 39, Issue 1, pp. 80-6, (2007) (PubMed).

Ojima, Inoue, Miki, Mori, Kusunoki: "Effectiveness of gene expression profiling for response prediction of rectal cancer to preoperative radiotherapy." in: Journal of gastroenterology, Vol. 42, Issue 9, pp. 730-6, (2007) (PubMed).

Clement, Johansson, Wolff, Park: "Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells." in: The FEBS journal, Vol. 273, Issue 6, pp. 1102-14, (2006) (PubMed).

Andersen, Lam, Leung, Ong, Lyon, Lamond, Mann: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, (2005) (PubMed).

Guan, Fung, Ma, Lau, Tai, Xie, Zhang, Hu, Wu, Fang, Sham: "Oncogenic role of eIF-5A2 in the development of ovarian cancer." in: Cancer research, Vol. 64, Issue 12, pp. 4197-200, (2004) (PubMed).

Synonyms and alternative names related to EIF5A2

eukaryotic translation initiation factor 5A2 (EIF5A2), eukaryotic translation initiation factor 5A2 (eif5a2), eukaryotic translation initiation factor 5A3 (LOC100499632), eukaryotic translation initiation factor 5A2 (Eif5a2), 9630038B20, EIF-5A2, EIF5A, EIF5A2, eIF5AII, wu:fb05b06, wu:fc23f04, wu:fc61c10, zgc:55504, zgc:77429

Protein level used designations for EIF5A2

  • eukaryotic translation initiation factor 5A-2
  • eukaryotic translation initiation factor 5A2
  • eukaryotic translation initiation factor 5A
  • eukaryotic translation initiation factor 5A3
  • eIF-5A-2
  • eukaryotic initiation factor 5A
  • eIF-5A2
  • eIF-4D
  • initiation factor 5A
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