EIF4G2 Products
(Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
Categories
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3\; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008].
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Featured EIF4G2 Categories
EIF4G2 Antibodies
High quality antibodies with extensive validation data.
EIF4G2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EIF4G2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (6)
Cat. No.
ABIN2855137
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (6)
Cat. No.
ABIN3016941
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN560721
Quantity
100 μg
Datasheet
Datasheet
Recommended EIF4G2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352618
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093105
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135559
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our EIF4G2 products
: "The mammalian host protein DAP5 facilitates the initial round of translation of Coxsackievirus B3 RNA." in: The Journal of biological chemistry, Vol. 294, Issue 42, pp. 15386-15394, (2019) (PubMed).: "The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 12, pp. 3585-601, (2014) (PubMed).
: "Thyroid hormone increases bulk histones expression by enhancing translational efficiency." in: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 1, pp. 68-75, (2014) (PubMed).
: "Amino acid availability and age affect the leucine stimulation of protein synthesis and eIF4F formation in muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 293, Issue 6, pp. E1615-21, (2007) (PubMed).
: "A new translational regulator with homology to eukaryotic translation initiation factor 4G." in: The EMBO journal, Vol. 16, Issue 4, pp. 817-25, (1997) (PubMed).
: "A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme." in: Genes & development, Vol. 11, Issue 3, pp. 321-33, (1997) (PubMed).
Synonyms and alternative names related to EIF4G2
eukaryotic translation initiation factor 4 gamma 2 (EIF4G2), eukaryotic translation initiation factor 4, gamma 2b (eif4g2b), eukaryotic translation initiation factor 4, gamma 2 (Eif4g2), eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), eIF4G-related protein NAT1 (nat1), eukaryotic translation initiation factor 4 gamma 2 (Eif4g2), eukaryotic translation initiation factor 4, gamma 2a (eif4g2a), eukaryotic translation initiation factor 4 gamma, 2 S homeolog (eif4g2.S), AA589388, AAG1, DAP-5, DAP5, dap5, E130105L11Rik, eif4g2, EIF4G2, eif4g2.L, hm:zeh1307, im:7148615, NAT1, Nat1, nat1, NAT1A, NAT1B, Natm1, P97, p97, wu:fa14h01, wu:fb44h01, wu:fb59c06, wu:fb81f07, wu:fb82b06, wu:fb98h08, wu:fc21b05Protein level used designations for EIF4G2
- DAP-5
- aging-associated protein 1
- death-associated protein 5
- eIF-4-gamma 2
- eIF-4G 2
- eIF4G 2
- eukaryotic translation initiation factor 4 gamma 2
- eukaryotic translation initiation factor 4G-like 1
- p97
- novel APOBEC-1 target 1
- translation repressor NAT1
- eukaryotic translation initiation factor 4 gamma, 2
- fb44h01
- Eukaryotic translation initiation factor 4 gamma 2
- translation repressor Nat1
- eIF4G-related protein NAT1
- eIF4G-related protein NAT1A
- eukaryotic translation initiation factor 4, gamma 2a
- eukaryotic translation initiation factor 4 gamma, 2 L homeolog
- eukaryotic translation initiation factor 4 gamma, 2 S homeolog
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