EIF4G1 Products
(Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
Categories
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured EIF4G1 Categories
EIF4G1 Antibodies
High quality antibodies with extensive validation data.
EIF4G1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EIF4G1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (7)
Cat. No.
ABIN515213
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
Cat. No.
ABIN515212
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7263569
Quantity
200 μL
Datasheet
Datasheet
Recommended EIF4G1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6228193
Quantity
96 tests
Datasheet
Datasheet
Recommended EIF4G1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1352615
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352616
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2720102
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our EIF4G1 products
: "Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia." in: American journal of physiology. Endocrinology and metabolism, Vol. 311, Issue 4, pp. E791-E801, (2016) (PubMed).: "DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation." in: Nucleic acids research, Vol. 43, Issue 7, pp. 3764-75, (2015) (PubMed).
: "Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA." in: Molecular and cellular biology, Vol. 34, Issue 3, pp. 439-51, (2014) (PubMed).
: "Dynamic regulation of the translation initiation helicase complex by mitogenic signal transduction to eukaryotic translation initiation factor 4G." in: Molecular and cellular biology, Vol. 33, Issue 5, pp. 937-46, (2013) (PubMed).
: "Anabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E674-86, (2012) (PubMed).
: "A cellular response linking eIF4AI activity to eIF4AII transcription." in: RNA (New York, N.Y.), Vol. 18, Issue 7, pp. 1373-84, (2012) (PubMed).
: "Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 3, pp. 1046-51, (2011) (PubMed).
: "Phosphorylation of eukaryotic translation initiation factor 4G1 (eIF4G1) by protein kinase C{alpha} regulates eIF4G1 binding to Mnk1." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2947-59, (2011) (PubMed).
: "Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs." in: The Journal of nutrition, Vol. 141, Issue 12, pp. 2152-8, (2011) (PubMed).
: "Dysregulation of mTOR signaling in fragile X syndrome." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 2, pp. 694-702, (2010) (PubMed).
Synonyms and alternative names related to EIF4G1
eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), eukaryotic translation initiation factor 4G (eIF4G), eukaryotic translation initiation factor 4 gamma, 1a (eif4g1a), eukaryotic translation initiation factor 4 gamma 1 (LOC704923), eukaryotic translation initiation factor 4 gamma, 1 S homeolog (eif4g1.S), eukaryotic translation initiation factor 4G (EIF4G), eukaryotic initiation factor (EIF4G), eukaryotic translation initiation factor 4 gamma (eIF4g), eukaryotic translation initiation factor 4 gamma (Eif4g), eukaryotic translation initiation factor 4 gamma, 1 (Eif4g1), eukaryotic translation initiation factor 4, gamma 1 (Eif4g1), CG10811, CUCUMOVIRUS MULTIPLICATION 2, CUM2, DDBDRAFT_0217646, DDBDRAFT_0217647, DDBDRAFT_0234257, DDB_0217646, DDB_0217647, DDB_0234257, deIF4G, Dmel\\CG10811, E030015G23Rik, eIF-4G, EIF-4G1, EIF4F, EIF4G, Eif4G, eIF4g, eif4g, EIF4G1, EIF4GI, eIF4GI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, eukaryotic translation initiation factor 4G, NV18824, p200, P220, p220, PARK18, wu:fb50a05, wu:fc60b06Protein level used designations for EIF4G1
- eukaryotic translation initiation factor 4 gamma 1
- CG10811-PA
- CG10811-PB
- CG10811-PC
- Eukaryotic-initiation-factor-4G
- eIF-4G
- eIF4G-PA
- eIF4G-PB
- eIF4G-PC
- eukaryotic initiation factor 4G
- translation initiation factor
- translation initiation factor eIF4G
- eukaryotic translation initiation factor 4 gamma, 1
- fb50a05
- eukaryotic initiation factor
- eukaryotic translation initiation factor 4 gamma
- eukaryotic translation initiation factor 4 gamma 1-like
- EIF4-gamma
- eIF-4-gamma 1
- eucaryotic translation initiation factor 4G
- eIF-4G 1
- eIF-4G1
You are here:
