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EIF4ENIF1 Products

(Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1 (EIF4ENIF1))

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The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic\; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].

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Featured EIF4ENIF1 Categories

EIF4ENIF1 Antibodies

High quality antibodies with extensive validation data.

EIF4ENIF1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF4ENIF1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (5)
Cat. No. ABIN527919
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN527918
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7267051
Quantity 100 μL
Datasheet Datasheet

Recommended EIF4ENIF1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352613
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088011
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137234
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our EIF4ENIF1 products

Amadei, Zander, Yang, Dumelie, Vessey, Lipshitz, Smibert, Kaplan, Miller: "A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 47, pp. 15666-81, (2015) (PubMed).

Martínez, Sesé, Losa, Robichaud, Sonenberg, Aasen, Ramón Y Cajal: "Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123352, (2015) (PubMed).

Yang, Smibert, Kaplan, Miller: "An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program." in: Neuron, Vol. 84, Issue 4, pp. 723-39, (2014) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Dostie, Ferraiuolo, Pause, Adam, Sonenberg: "A novel shuttling protein, 4E-T, mediates the nuclear import of the mRNA 5' cap-binding protein, eIF4E." in: The EMBO journal, Vol. 19, Issue 12, pp. 3142-56, (2000) (PubMed).

Cyr, Langer, Douglas: "DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70." in: Trends in biochemical sciences, Vol. 19, Issue 4, pp. 176-81, (1994) (PubMed).

Craig, Gross: "Is hsp70 the cellular thermometer?" in: Trends in biochemical sciences, Vol. 16, Issue 4, pp. 135-40, (1991) (PubMed).

Singh, Yu: "Accumulation of a heat shock-like protein during differentiation of human erythroid cell line K562." in: Nature, Vol. 309, Issue 5969, pp. 631-3, (1984) (PubMed).

Synonyms and alternative names related to EIF4ENIF1

eukaryotic translation initiation factor 4E nuclear import factor 1 (Eif4enif1), eukaryotic translation initiation factor 4E nuclear import factor 1 (EIF4ENIF1), eukaryotic translation initiation factor 4E nuclear import factor 1 S homeolog (eif4enif1.S), eukaryotic translation initiation factor 4E nuclear import factor 1 (eif4enif1), 4E-T, 2610509L04Rik, A930019J01Rik, AA410001, AU021239, Clast4, D11Ertd166e, eif4enif1, EIF4ENIF1, MGC80355, MGC147579, RGD1560908, wu:fd15a05, zgc:101646

Protein level used designations for EIF4ENIF1

  • eukaryotic translation initiation factor 4E transporter
  • eukaryotic translation initiation factor 4E nuclear import factor 1
  • fd15a05
  • eukaryotic translation initiation factor 4E transporter-like
  • 2610509L04Rik
  • eIF4E transporter
  • eIF4E-transporter
  • 4E-T
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