eIF4EBP1 Products
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Categories
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].
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Featured eIF4EBP1 Categories
eIF4EBP1 Antibodies
High quality antibodies with extensive validation data.
eIF4EBP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
eIF4EBP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended eIF4EBP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Validations
- (5)
Cat. No.
ABIN682978
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, FACS, ICC
Validations
- (5)
Cat. No.
ABIN5611114
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
- (4)
Cat. No.
ABIN3021844
Quantity
100 μL
Datasheet
Datasheet
Recommended eIF4EBP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380515
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380514
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380149
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended eIF4EBP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122851
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352602
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2129067
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our eIF4EBP1 products
: "20(s)-Protopanaxadiol (PPD) increases the radiotherapy sensitivity of laryngeal carcinoma." in: Food & function, Vol. 8, Issue 12, pp. 4469-4477, (2018) (PubMed).: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).
: "Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer." in: Cell death & disease, Vol. 9, Issue 2, pp. 137, (2018) (PubMed).
: "Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR ..." in: Frontiers in molecular neuroscience, Vol. 10, pp. 68, (2017) (PubMed).
: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." in: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).
: "Association of maternal mRNA and phosphorylated EIF4EBP1 variants with the spindle in mouse oocytes: localized translational control supporting female meiosis in mammals." in: Genetics, Vol. 195, Issue 2, pp. 349-58, (2014) (PubMed).
: "Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells." in: PLoS ONE, Vol. 8, Issue 7, pp. e69104, (2013) (PubMed).
: "Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation." in: Journal of clinical immunology, Vol. 33, Issue 5, pp. 954-64, (2013) (PubMed).
: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).
: "Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice." in: PLoS ONE, Vol. 7, Issue 6, pp. e38910, (2012) (PubMed).
Synonyms and alternative names related to eIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1), eukaryotic translation initiation factor 4E binding protein 1 (Eif4ebp1), CG8846 gene product from transcript CG8846-RA (Thor), eukaryotic translation initiation factor 4E binding protein 1 (eif4ebp1), 4E-BP, 4e-bp, 4E-BP1, 4e-bp1, 4EBP, 4eBP, 4ebp, 4EBP1, 43-BP, 153432_at, AA959816, anon-WO0172774.158, BcDNA.HL08053, BcDNA:HL08053, BP-1, CG8846, CT8705, d4E-BP, d4e-bp, d4E-BP1, d4EBP, d4eBP, Dm 4E-BP, Dmel\\CG8846, dthor, eIF4E-BP, EIF4EBP1, fc04h09, l(2)06270, l(2)k07736, l(2)k13517, PHAS-I, Phas1, pp20, thor, Thor/EIF4EBP, wu:fc04h09, zgc:64137Protein level used designations for eIF4EBP1
- eIF4E-binding protein 1
- eukaryotic translation initiation factor 4E-binding protein 1
- phosphorylated heat- and acid-stable protein regulated by insulin 1
- 4E-BP1
- CG8846-PA
- Eif4e-binding protein
- Thor-PA
- eIF-4E-binding protein
- eif4e-binding protein 4EBP
- eukaryotic initiation factor 4E binding protein
- eukaryotic initiation factor 4E-binding protein
- eukaryotic translation initiation factor 4E binding protein
- eukaryotic translation initiation factor 4E-binding protein
- insulin-stimulated eIF-4E binding protein
- lethal (2) 06270
- thor
- eukaryotic translation initiation factor 4E binding protein 1
- translation initiation factor 4E binding protein 1
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