EIF2B3 Products
(Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))
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The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Featured EIF2B3 Categories
EIF2B3 Antibodies
High quality antibodies with extensive validation data.
EIF2B3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EIF2B3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, FACS
Validations
- (3)
Cat. No.
ABIN6243199
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN522375
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN7186610
Quantity
100 μg
Datasheet
Datasheet
Recommended EIF2B3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6216791
Quantity
96 tests
Datasheet
Datasheet
Recommended EIF2B3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352514
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079377
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2720068
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our EIF2B3 products
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter." in: Annals of neurology, Vol. 51, Issue 2, pp. 264-70, (2002) (PubMed).
: "Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation ..." in: Molecular and cellular biology, Vol. 20, Issue 11, pp. 3965-76, (2000) (PubMed).
: "Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 15, pp. 8566-71, (2000) (PubMed).
Synonyms and alternative names related to EIF2B3
eukaryotic translation initiation factor 2B subunit gamma L homeolog (eif2b3.L), eukaryotic translation initiation factor 2B, subunit 3 gamma (eif2b3), eukaryotic translation initiation factor 2B subunit gamma (EIF2B3), eukaryotic translation initiation factor 2B subunit gamma (eif2b3), eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (Eif2b3), eukaryotic translation initiation factor 2B subunit gamma (Eif2b3), eukaryotic translation initiation factor 2B, subunit 3 (Eif2b3), 1190002P15Rik, EIF-2B, EIF2Bgamma, zgc:56473Protein level used designations for EIF2B3
- eukaryotic translation initiation factor 2B, subunit 3 gamma
- translation initiation factor eIF-2B subunit gamma
- eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
- Translation initiation factor eIF-2B subunit gamma-like protein
- eIF2B-gamma protein
- translation initiation factor eIF-2B subunit gamma-like
- eIF-2B GDP-GTP exchange factor subunit gamma
- eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD)
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