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EFNB2A Antibodies

(EFNB2A)
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration (By similarity). {ECO:0000250}.

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Featured EFNB2A Categories

EFNB2A Antibodies

High quality antibodies with extensive validation data.

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Latest Publications for our EFNB2A products

Chan, Mably, Serluca, Chen, Goldstein, Thomas, Cleary, Brennan, Fishman, Roberts: "Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling." in: Developmental biology, Vol. 234, Issue 2, pp. 470-82, (2001) (PubMed).

Durbin, Brennan, Shiomi, Cooke, Barrios, Shanmugalingam, Guthrie, Lindberg, Holder: "Eph signaling is required for segmentation and differentiation of the somites." in: Genes & development, Vol. 12, Issue 19, pp. 3096-109, (1998) (PubMed).

Synonyms and alternative names related to EFNB2A

ephrin-B2a (efnb2a), efnb2, id:ibd5072

Protein level used designations for EFNB2A

  • ephrin-B2a
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