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EFCAB4B Proteins

(EF-Hand Calcium Binding Domain 4B (EFCAB4B))

Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).

recommended

EFCAB4B Protein (AA 1-395) (GST tag) (ABIN1352375)

EFCAB4B Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB

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recommended

EFCAB4B Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2719954)

EFCAB4B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

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EFCAB4B Proteins by Origin

Find EFCAB4B Proteins for a variety of species such as anti-Human EFCAB4B. The species listed below are among those available. Click on a link to go to the corresponding products.

EFCAB4B Proteins by Source

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EFCAB4B Proteins by Protein Type

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EFCAB4B Proteins by Application

Find EFCAB4B Proteins validated for a specific application such as AP, AA, AbP, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular EFCAB4B Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

EFCAB4B Protein (AA 1-395) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1352375

Quantity 10 μg

Datasheet Datasheet

EFCAB4B Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719954

Quantity 20 μg

Datasheet Datasheet

Aliases for EFCAB4B Proteins

calcium release activated channel regulator 2A (CRACR2A) Proteins
calcium release activated channel regulator 2A (Cracr2a) Proteins
CRACR2A Proteins
Gm462 Proteins
Gm1073 Proteins

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EFCAB4B Proteins by Origin

EFCAB4B Proteins by Source

EFCAB4B Proteins by Protein Type

EFCAB4B Proteins by Application

Popular EFCAB4B Proteins

Aliases for EFCAB4B Proteins

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