EFCAB4B Products
(EF-Hand Calcium Binding Domain 4B (EFCAB4B))
Categories
Ca(2+)-binding protein that plays a key role in store- operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+) concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+) resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex (By similarity).
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Featured EFCAB4B Categories
EFCAB4B Antibodies
High quality antibodies with extensive validation data.
EFCAB4B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EFCAB4B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN6138999
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7257401
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN529776
Quantity
50 μg
Datasheet
Datasheet
Recommended EFCAB4B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6230048
Quantity
96 tests
Datasheet
Datasheet
Recommended EFCAB4B Proteins
Synonyms and alternative names related to EFCAB4B
calcium release activated channel regulator 2A (CRACR2A), calcium release activated channel regulator 2A (Cracr2a), CRACR2A, Gm462, Gm1073Protein level used designations for EFCAB4B
- CRAC channel regulator 2A
- EF-hand calcium-binding domain-containing protein 4B
- calcium release-activated calcium channel regulator 2A
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