EEF2K Products
(Eukaryotic Elongation Factor-2 Kinase (EEF2K))
Categories
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. {ECO:0000269|PubMed:14709557, ECO:0000269|PubMed:9144159}.
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Featured EEF2K Categories
EEF2K Antibodies
High quality antibodies with extensive validation data.
EEF2K ELISA Kits
Reliable ELISA kits for a wide range of species.
EEF2K Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EEF2K Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN6261444
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (4)
Cat. No.
ABIN2856812
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN526147
Quantity
50 μg
Datasheet
Datasheet
Recommended EEF2K ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966603
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380120
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended EEF2K Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
Cat. No.
ABIN1352365
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508902
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2129033
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our EEF2K products
: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).: "Eukaryotic elongation factor2 kinase controls proliferation and migration of vascular smooth muscle cells." in: Acta physiologica (Oxford, England), (2014) (PubMed).
: "Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma." in: PLoS ONE, Vol. 8, Issue 11, pp. e81345, (2013) (PubMed).
: "Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12220-31, (2004) (PubMed).
: "A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2986-97, (2004) (PubMed).
: "Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways." in: The Biochemical journal, Vol. 367, Issue Pt 2, pp. 525-32, (2002) (PubMed).
Synonyms and alternative names related to EEF2K
eukaryotic elongation factor 2 kinase (EEF2K), eukaryotic elongation factor-2 kinase (Eef2k), eukaryotic elongation factor 2 kinase (eef2k), eukaryotic elongation factor 2 kinase (LOC101930123), eukaryotic elongation factor 2 kinase (Eef2k), C86191, cb365, eEF-2 kinase, eEF-2K, fa04b08, HSU93850, SMEF2K, wu:fa04b08, zgc:100973Protein level used designations for EEF2K
- calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
- calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase
- calmodulin-dependent protein kinase III
- eEF-2 kinase
- elongation factor-2 kinase
- eukaroytic elongation factor 2 kinase
- eukaryotic elongation factor 2 kinase
- eukaryotic elongation factor-2 kinase
- eukaroytic elongation factor 2 kinase-like
- eEF-2K
- elongation factor 2 kinase
- Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
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