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EDEM1 Products

(ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Categories

Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.

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Featured EDEM1 Categories

EDEM1 Antibodies

High quality antibodies with extensive validation data.

EDEM1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EDEM1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN523170
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7151970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6261429
Quantity 100 μL
Datasheet Datasheet

Recommended EDEM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352310
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3117060
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136915
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our EDEM1 products

Molinari, Calanca, Galli, Lucca, Paganetti: "Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle." in: Science (New York, N.Y.), Vol. 299, Issue 5611, pp. 1397-400, (2003) (PubMed).

Nagase, Seki, Ishikawa, Ohira, Kawarabayasi, Ohara, Tanaka, Kotani, Miyajima, Nomura: "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 3, Issue 5, pp. 321-9, 341-54, (1997) (PubMed).

Synonyms and alternative names related to EDEM1

ER degradation enhancer, mannosidase alpha-like 1 (edem1), ER degradation enhancing alpha-mannosidase like protein 1 (edem1), ER degradation enhancing alpha-mannosidase like protein 1 (EDEM1), ER degradation-enhancing alpha-mannosidase-like protein 1 (LOC100637820), ER degradation enhancing alpha-mannosidase like protein 1 L homeolog (edem1.L), ER degradation enhancer, mannosidase alpha-like 1 (Edem1), ER degradation enhancing alpha-mannosidase like protein 1 (Edem1), A130059K23Rik, edem, EDEM, EDEM1, mKIAA0212, RGD1563633, zgc:55816

Protein level used designations for EDEM1

  • ER degradation-enhancing alpha-mannosidase-like 1
  • ER degradation enhancer, mannosidase alpha-like 1
  • ER degradation-enhancing alpha-mannosidase-like 1-like
  • ER degradation-enhancing alpha-mannosidase-like protein 1
  • ER degradation ER degradation enhancer, mannosidase alpha-like 1
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