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Ectodysplasin A2 Receptor Products

(Ectodysplasin A2 Receptor (EDA2R))

Categories

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2011].

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Featured Ectodysplasin A2 Receptor Categories

Ectodysplasin A2 Receptor Antibodies

High quality antibodies with extensive validation data.

Ectodysplasin A2 Receptor ELISA Kits

Reliable ELISA kits for a wide range of species.

Ectodysplasin A2 Receptor Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ectodysplasin A2 Receptor Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN7193350
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7173881
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN528408
Quantity 100 μg
Datasheet Datasheet

Recommended Ectodysplasin A2 Receptor ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955497
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1164409
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5653777
Quantity 96 tests
Datasheet Datasheet

Recommended Ectodysplasin A2 Receptor Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274510
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274509
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320722
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Ectodysplasin A2 Receptor products

Staropoli, Li, Chun, Allaire, Cullen, Thai, Fleet, Hua, Bennett, Krainer, Kerr, McCampbell, Rigo, Carulli: "Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7." in: Genomics, Vol. 105, Issue 4, pp. 220-8, (2015) (PubMed).

Westland, Verbitsky, Vukojevic, Perry, Fasel, Zwijnenburg, Bökenkamp, Gille, Saraga-Babic, Ghiggeri, DAgati, Schreuder, Gharavi, van Wijk, Sanna-Cherchi: "Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney." in: Kidney international, Vol. 88, Issue 6, pp. 1402-1410, (2015) (PubMed).

Sinha, Chaudhary: "Induction of apoptosis by X-linked ectodermal dysplasia receptor via a caspase 8-dependent mechanism." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41873-81, (2004) (PubMed).

Sinha, Zachariah, Quiñones, Shindo, Chaudhary: "Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 44953-61, (2002) (PubMed).

Yan, Wang, Hymowitz, Schilbach, Lee, Goddard, de Vos, Gao, Dixit: "Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors." in: Science (New York, N.Y.), Vol. 290, Issue 5491, pp. 523-7, (2000) (PubMed).

Synonyms and alternative names related to Ectodysplasin A2 Receptor

ectodysplasin A2 receptor (EDA2R), ectodysplasin A2 receptor (Eda2r), 9430060M22Rik, EDA-A2R, EDAA2R, RGD1564025, TNFRSF27, XEDAR, Xedar

Protein level used designations for Ectodysplasin A2 Receptor

  • X-linked ectodysplasin receptor
  • tumor necrosis factor receptor superfamily member 27
  • xedar
  • ectodysplasin A2 receptor
  • EDA-A2 receptor
  • X-linked ectodysplasin-A2 receptor
  • tumor necrosis factor receptor superfamily member XEDAR
  • X linked ectodysplasin receptor
  • ectodysplasin A2 isoform receptor
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