E2F6 Products
(E2F Transcription Factor 6 (E2F6))
Categories
This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq, Jul 2008].
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Featured E2F6 Categories
E2F6 Antibodies
High quality antibodies with extensive validation data.
E2F6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended E2F6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (1)
- (4)
Cat. No.
ABIN6261413
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP, ChIP
Validations
- (4)
Cat. No.
ABIN1679632
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7234987
Quantity
200 μL
Datasheet
Datasheet
Recommended E2F6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352242
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079106
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131804
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our E2F6 products
: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).: "Human papillomavirus type 16 E7 oncoprotein associates with E2F6." in: Journal of virology, Vol. 82, Issue 17, pp. 8695-705, (2008) (PubMed).
: "A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members." in: Genome research, Vol. 17, Issue 11, pp. 1550-61, (2007) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyms and alternative names related to E2F6
E2F transcription factor 6 (E2F6), E2F transcription factor 6 (E2f6), AI462434, E2F-6, E2F6b, EMAProtein level used designations for E2F6
- E2F transcription factor 6
- transcription factor E2F6
- E2F-6
- E2F-binding site-modulating activity protein
- transcriptional repressor E2F6
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