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E2F3 Products

(E2F3)

Categories

This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].

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Featured E2F3 Categories

E2F3 Antibodies

High quality antibodies with extensive validation data.

E2F3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended E2F3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (5)
Cat. No. ABIN560679
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (3)
  • (4)
Cat. No. ABIN2780388
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (1)
Cat. No. ABIN733493
Quantity 100 μL
Datasheet Datasheet

Recommended E2F3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955491
Quantity 96 tests
Datasheet Datasheet

Recommended E2F3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352235
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352237
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409278
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our E2F3 products

Pozner, Terooatea, Buck-Koehntop: "Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24538-24550, (2017) (PubMed).

Yang, Wang, Tang, Bai: "miR-203a suppresses cell proliferation by targeting E2F transcription factor 3 in human gastric cancer." in: Oncology letters, Vol. 14, Issue 6, pp. 7687-7690, (2017) (PubMed).

Geng, Song, Ning, Song, Yin: "MiR-34a Inhibits Viability and Invasion of Human Papillomavirus-Positive Cervical Cancer Cells by Targeting E2F3 and Regulating Survivin." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 25, Issue 4, pp. 707-13, (2015) (PubMed).

Tarangelo, Lo, Teng, Kim, Le, Watson, Furth, Raman, Ehmer, Viatour: "Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression." in: Nature communications, Vol. 6, pp. 10028, (2015) (PubMed).

Giangreco, Vaishnav, Wagner, Finelli, Fleshner, Van der Kwast, Vieth, Nonn: "Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 5, pp. 483-94, (2013) (PubMed).

Yu, Lu, Zuo, Yan, Yu, Li, Huang, Zhao, Tang, Luo, Liao, Zeng, Zhang, Li: "Epstein-Barr virus downregulates microRNA 203 through the oncoprotein latent membrane protein 1: a contribution to increased tumor incidence in epithelial cells." in: Journal of virology, Vol. 86, Issue 6, pp. 3088-99, (2012) (PubMed).

Melcher, Hartmann, Zopf, Herterich, Wilke, Müller, Rosler, Kudlich, Al-Taie, Rosenwald, Katzenberger, Scholtka, Seibold, Rogoll, Scheppach, Scheurlen, Lührs: "LOH and copy neutral LOH (cnLOH) act as alternative mechanism in sporadic colorectal cancers with chromosomal and microsatellite instability." in: Carcinogenesis, Vol. 32, Issue 4, pp. 636-42, (2011) (PubMed).

Wang, Li, Zhang, Li, Yue, Xie, Xie: "Regulating A549 cells growth by ASO inhibiting miRNA expression." in: Molecular and cellular biochemistry, Vol. 339, Issue 1-2, pp. 163-71, (2010) (PubMed).

Xie, Li, Wang, Jiao, Zhang, Zhang: "miRNA-regulated expression of oncogenes and tumor suppressor genes in the cisplatin-inhibited growth of K562 cells." in: Oncology reports, Vol. 23, Issue 6, pp. 1693-700, (2010) (PubMed).

Naga Prasad, Duan, Gupta, Surampudi, Volinia, Calin, Liu, Kotwal, Moravec, Starling, Perez, Sen, Wu, Plow, Croce, Karnik: "Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks." in: The Journal of biological chemistry, Vol. 284, Issue 40, pp. 27487-99, (2009) (PubMed).

Synonyms and alternative names related to E2F3

E2F transcription factor 3 (E2F3), E2F transcription factor 3 S homeolog (e2f3.S), E2F transcription factor 3 (E2f3), E2F-3, E2f3a, E2F3b, mKIAA0075, RGD1561600

Protein level used designations for E2F3

  • transcription factor E2F3
  • transcription factor E2F
  • E2F-3
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