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E-cadherin Products

(Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

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This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].

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Featured E-cadherin Categories

E-cadherin Antibodies

High quality antibodies with extensive validation data.

E-cadherin ELISA Kits

Reliable ELISA kits for a wide range of species.

E-cadherin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended E-cadherin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
Validations
  • (14)
  • (12)
  • (1)
Cat. No. ABIN1387847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP, ICC, IHC (p), IHC (wm)
Validations
  • (10)
  • (8)
Cat. No. ABIN2854751
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (19)
  • (5)
Cat. No. ABIN6261408
Quantity 100 μL
Datasheet Datasheet

Recommended E-cadherin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954244
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6963429
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965292
Quantity 96 tests
Datasheet Datasheet

Recommended E-cadherin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7092826
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7092842
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348882
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our E-cadherin products

Autenshlyus, Bernado, Studenikina, Proskura, Davletova, Zhurakovskiy, Arkhipov, Varaksin, Sidorov, Lyakhovich et al.: "Personalized Approach to Determination of Histidine-Rich Glycoprotein and E-Cadherin in Supernatants of Immunocompetent Blood Cells and Breast Biopsy Specimens in Breast Malignant and Non-Malignant ..." in: Doklady. Biochemistry and biophysics, Vol. 490, Issue 1, pp. 1-4, (2021) (PubMed).

Meng, Lu, Zhou, Zhang, Gao, Gao, Yan, Liang: "Characterization of the prognostic values and response to immunotherapy/chemotherapy of Krüppel-like factors in prostate cancer." in: Journal of cellular and molecular medicine, Vol. 24, Issue 10, pp. 5797-5810, (2021) (PubMed).

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Bray, Elgamal, Jiang, Wright, Sutaria, Badawi, Borcyk, Liu, Fredenburg, Campbell-Thompson, Schmittgen: "Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury." in: Cell death & disease, Vol. 11, Issue 2, pp. 138, (2020) (PubMed).

Kaban, Salva, Akbuga: "Modulation of the dual-faced effects of miR-141 with chitosan/miR-141 nanoplexes in breast cancer cells." in: The journal of gene medicine, Vol. 21, Issue 9, pp. e3116, (2020) (PubMed).

Verma, Kang, Pal, Gupta: "BST2 regulates interferon gamma-dependent decrease in invasion of HTR-8/SVneo cells via STAT1 and AKT signaling pathways and expression of E-cadherin." in: Cell adhesion & migration, Vol. 14, Issue 1, pp. 24-41, (2020) (PubMed).

El-Dawla, Sallam, El-Hefnawy, El-Mesallamy: "E-cadherin and periostin in early detection and progression of diabetic nephropathy: epithelial-to-mesenchymal transition." in: Clinical and experimental nephrology, Vol. 23, Issue 8, pp. 1050-1057, (2020) (PubMed).

Shetti, Zhang, Fan, Mo, Lee, Wei: "Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling." in: Cells, Vol. 8, Issue 8, (2020) (PubMed).

OBrien, Dorsey, Hannan, Hultgren: "Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner." in: PLoS pathogens, Vol. 14, Issue 12, pp. e1007457, (2019) (PubMed).

London, Tharakan, Mendiola, Sussan, Chen, Dobzanski, Lane, Sidhaye, Biswal, Ramanathan: "Deletion of Nrf2 enhances susceptibility to eosinophilic sinonasal inflammation in a murine model of rhinosinusitis." in: International forum of allergy & rhinology, Vol. 9, Issue 1, pp. 114-119, (2019) (PubMed).

Synonyms and alternative names related to E-cadherin

cadherin 1 (CDH1), si:busm1-180o5.2 (si:busm1-180o5.2), cadherin 1, type 1, E-cadherin (epithelial) (cdh1), cadherin 1 (Cdh1), cadherin 1, type 1 S homeolog (cdh1.S), AA960649, Arc-1, arc-1, c-cadherin, cadherin-1, CD324, cd324, cdh1, cdhc-A, CDHE, cdhe, E-Cad, E-cad, E-cadherin, ECAD, ecad, Ecad, l-cam, L-CAM, LCAM, lcam, si:dz180o5.2, Um, UVO, uvo, uvomorulin, xb-cad, XB-cadherin, XBcad, xcdh1, XTCAD-1

Protein level used designations for E-cadherin

  • CAM 120/80
  • E-Cadherin
  • cadherin 1, E-cadherin (epithelial)
  • cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • cell-CAM 120/80
  • epithelial cadherin
  • uvomorulin
  • hypothetical protein LOC368517
  • cadherin 1, epithelial
  • hab
  • half baked
  • E-cadherin
  • cadherin 1, type 1, E-cadherin (epithelial)
  • xTCAD-1
  • ARC-1
  • L-CAM
  • liver cell adhesion molecule
  • liver cell adhesion protein
  • Epithelial cadherin
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