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Dystrophin Proteins

(Dystrophin (DMD))

The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].

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Dystrophin Protein (DMD) (AA 1-635) (GST tag) (ABIN1351717)

DMD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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DMD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

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DMD Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

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Dystrophin Proteins by Origin

Find Dystrophin Proteins for a variety of species such as anti-Human Dystrophin, anti-Mouse Dystrophin. The species listed below are among those available. Click on a link to go to the corresponding products.

Dystrophin Proteins by Source

Here you will find Dystrophin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Dystrophin Proteins by Protein Type

Here you can find Dystrophin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Dystrophin Proteins by Application

Find Dystrophin Proteins validated for a specific application such as WB, SDS, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Dystrophin Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Dystrophin Protein (DMD) (AA 1-635) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351717

Quantity 10 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 253-597) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7420834

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 3048-3328) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394210

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (AA 3059-3314) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394213

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN3009210

Quantity 100 μg

Datasheet Datasheet

Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719890

Quantity 20 μg

Datasheet Datasheet

Aliases for Dystrophin Proteins

dystrophin (DMD) Proteins
dystrophin (LOC708073) Proteins
dystrophin, gene 1 L homeolog (dmd.1.L) Proteins
dystrophin (LOC465557) Proteins
dystrophin, gene 1 (dmd.1) Proteins
dystrophin (dmd) Proteins
dystrophin, muscular dystrophy (Dmd) Proteins
dystrophin (Dmd) Proteins
Dystrophin (Dys) Proteins
BMD Proteins
cb664 Proteins
CG7240 Proteins
CG7243 Proteins
CG7344 Proteins
CG17750 Proteins
CG31175 Proteins
CG34157 Proteins
CMD3B Proteins
det Proteins
DKFZp459C1629 Proteins
DKFZp468A1620 Proteins
DLP Proteins
DLP1 Proteins
DLP2 Proteins
DLP3 Proteins
DLP186 Proteins
DMD Proteins
Dmd Proteins
dmd Proteins
DmDLP Proteins
dmDLP Proteins
dmDp186 Proteins
DmDYS Proteins
dmDys Proteins
Dmel\\CG34157 Proteins
DNADMD1 Proteins
Dp71 Proteins
Dp117 Proteins
Dp186 Proteins
Dp205 Proteins
Dp427 Proteins
DXS142 Proteins
DXS164 Proteins
DXS206 Proteins
DXS230 Proteins
DXS239 Proteins
DXS268 Proteins
DXS269 Proteins
DXS270 Proteins
DXS272 Proteins
DXSmh7 Proteins
DXSmh9 Proteins
dys Proteins
GI3046716 Proteins
IDLP Proteins
im:6911785 Proteins
mdx Proteins
MGC79631 Proteins
MGC83347 Proteins
pke Proteins
RATDMD Proteins
zfDYS Proteins
zgc:110165 Proteins

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Dystrophin Proteins by Origin

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Dystrophin Proteins by Application

Popular Dystrophin Proteins

Aliases for Dystrophin Proteins

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