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DYRK1B Products

(Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

Categories

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain. [provided by RefSeq, Jul 2008].

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Featured DYRK1B Categories

DYRK1B Antibodies

High quality antibodies with extensive validation data.

DYRK1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DYRK1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN522612
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257023
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
  • (2)
Cat. No. ABIN391774
Quantity 400 μL
Datasheet Datasheet

Recommended DYRK1B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6223257
Quantity 96 tests
Datasheet Datasheet

Recommended DYRK1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352204
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352202
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508898
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DYRK1B products

Gao, Zhao, Lv, Chen, Wei, Tian, Yang, Kong, Pang, Liu, Shi: "Mirk/Dyrk1B mediates G0/G1 to S phase cell cycle progression and cell survival involving MAPK/ERK signaling in human cancer cells." in: Cancer cell international, Vol. 13, Issue 1, pp. 2, (2013) (PubMed).

Gao, Yang, Yin, Hu, Liao, Miao, Pan, Li: "The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer." in: International journal of oncology, Vol. 40, Issue 4, pp. 1203-9, (2012) (PubMed).

Lee, Ha, Kim, Kim, Chang, Song, Kim: "Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33343-51, (2009) (PubMed).

Takahashi-Yanaga, Mori, Matsuzaki, Watanabe, Hirata, Miwa, Morimoto, Sasaguri: "Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38489-97, (2006) (PubMed).

Lim, Zou, Friedman: "The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49438-45, (2002) (PubMed).

Lim, Jin, Friedman: "Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha." in: The Journal of biological chemistry, Vol. 277, Issue 28, pp. 25040-6, (2002) (PubMed).

Lee, Deng, Friedman: "Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells." in: Cancer research, Vol. 60, Issue 13, pp. 3631-7, (2000) (PubMed).

Synonyms and alternative names related to DYRK1B

dual specificity tyrosine phosphorylation regulated kinase 1B (DYRK1B), dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b), DYRK1A, DYRK1B, MIRK, Mirk

Protein level used designations for DYRK1B

  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
  • dual specificity tyrosine-phosphorylation-regulated kinase 1B-like
  • dual specificity tyrosine-phosphorylation-regulated kinase 1B
  • minibrain-related kinase
  • mirk protein kinase
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
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