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DUSP7 Products

(Dual Specificity Phosphatase 7 (DUSP7))

Categories

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009].

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Featured DUSP7 Categories

DUSP7 Antibodies

High quality antibodies with extensive validation data.

DUSP7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DUSP7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7150785
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), ICC, IF
Validations
  • (3)
Cat. No. ABIN2856666
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392865
Quantity 400 μL
Datasheet Datasheet

Recommended DUSP7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352142
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3127538
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3079078
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DUSP7 products

Chappell, Sun, Singh, Dalton: "MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7." in: Genes & development, Vol. 27, Issue 7, pp. 725-33, (2013) (PubMed).

Orlev, Ehud, Tamar, Orit, Yoel, Witz: "Does the dual-specificity MAPK phosphatase Pyst2-L lead a monogamous relationship with the Erk2 protein?" in: Immunology letters, Vol. 92, Issue 1-2, pp. 149-56, (2004) (PubMed).

Levy-Nissenbaum, Sagi-Assif, Kapon, Hantisteanu, Burg, Raanani, Avigdor, Ben-Bassat, Witz: "Dual-specificity phosphatase Pyst2-L is constitutively highly expressed in myeloid leukemia and other malignant cells." in: Oncogene, Vol. 22, Issue 48, pp. 7649-60, (2003) (PubMed).

Levy-Nissenbaum, Sagi-Assif, Raanani, Avigdor, Ben-Bassat, Witz: "cDNA microarray analysis reveals an overexpression of the dual-specificity MAPK phosphatase PYST2 in acute leukemia." in: Methods in enzymology, Vol. 366, pp. 103-13, (2003) (PubMed).

Synonyms and alternative names related to DUSP7

dual specificity phosphatase 7 (DUSP7), dual specificity phosphatase 7 (dusp7), Dual specificity protein phosphatase 7 (dus7), dual specificity phosphatase 7 (Dusp7), AU015694, DUSP7, mkp-x, mkp-X, mkpx, MKPX, Mkpx, pyst2, PYST2, Pyst2

Protein level used designations for DUSP7

  • dual specificity phosphatase 7
  • dual specificity protein phosphatase 7-like
  • Dual specificity protein phosphatase 7
  • dual specificity protein phosphatase 7
  • dual specificity protein phosphatase PYST2
  • dual-specificity phosphatase-7
  • MAP kinase phosphatase
  • dual specificity protein phosphatase MKP-X
  • hypothetical protein
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