DUOX1 Products
(Dual Oxidase 1 (DUOX1))
Categories
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012].
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Featured DUOX1 Categories
DUOX1 Antibodies
High quality antibodies with extensive validation data.
DUOX1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DUOX1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DUOX1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7150689
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN1386159
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN263200
Quantity
100 μg
Datasheet
Datasheet
Recommended DUOX1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966424
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1130711
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Validations
Cat. No.
ABIN1130710
Quantity
96 tests
Datasheet
Datasheet
Recommended DUOX1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352080
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719809
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719810
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our DUOX1 products
: "Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism." in: PLoS ONE, Vol. 11, Issue 8, pp. e0159248, (2016) (PubMed).: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).
: "Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase." in: BMC systems biology, Vol. 5, pp. 164, (2011) (PubMed).
: "Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium." in: FEBS letters, Vol. 579, Issue 21, pp. 4911-7, (2005) (PubMed).
Synonyms and alternative names related to DUOX1
dual oxidase 1 (duox1), dual oxidase 1 (DUOX1), dual oxidase (duox), dual oxidase (LOC5569378), dual oxidase 1 (Duox1), 9930101G15Rik, AW987690, duox1, Duox2, LNOX1, LNOX2, NOXEF1, NOXEF2, P138-TOX, THOX1, THOX2, Udx1Protein level used designations for DUOX1
- dual oxidase 1
- NADPH thyroid oxidase 1
- flavoprotein NADPH oxidase
- large NOX 1
- long NOX 1
- nicotinamide adenine dinucleotide phosphate oxidase
- thyroid oxidase 1
- dual oxidase 2
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