DROSHA Products
(Drosha, Ribonuclease Type III (DROSHA))
Categories
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008].
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Featured DROSHA Categories
DROSHA Antibodies
High quality antibodies with extensive validation data.
DROSHA ELISA Kits
Reliable ELISA kits for a wide range of species.
DROSHA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DROSHA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (4)
Cat. No.
ABIN7188005
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN334479
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7264363
Quantity
200 μL
Datasheet
Datasheet
Recommended DROSHA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966423
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955459
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5658503
Quantity
96 tests
Datasheet
Datasheet
Recommended DROSHA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1318168
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN1691359
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397228
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DROSHA products
: "Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia." in: Leukemia, Vol. 29, Issue 1, pp. 86-95, (2015) (PubMed).: "DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs." in: Molecular cell, Vol. 60, Issue 6, pp. 873-85, (2015) (PubMed).
: "Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. ..." in: Nature communications, Vol. 5, pp. 5202, (2014) (PubMed).
: "Novel functional small RNAs are selectively loaded onto mammalian Ago1." in: Nucleic acids research, Vol. 42, Issue 8, pp. 5289-301, (2014) (PubMed).
: "Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin." in: Development (Cambridge, England), Vol. 139, Issue 8, pp. 1405-16, (2012) (PubMed).
: "WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway." in: Nucleic acids research, Vol. 39, Issue 10, pp. 4048-62, (2011) (PubMed).
: "Extensive post-transcriptional regulation of microRNAs and its implications for cancer." in: Genes & development, Vol. 20, Issue 16, pp. 2202-7, (2006) (PubMed).
Synonyms and alternative names related to DROSHA
ribonuclease type III, nuclear (rnasen), Ribonuclease 3 (Thicy_0885), Ribonuclease 3 (Sinme_0866), ribonuclease 3 (Isova_2087), Ribonuclease 3 (Sphch_0770), drosha ribonuclease III (DROSHA), drosha, ribonuclease type III (DROSHA), drosha, ribonuclease type III (Drosha), drosha ribonuclease III (Drosha), 1110013A17Rik, AI874853, ETOHI2, Etohi2, HSA242976, im:7150667, RANSE3L, RGD1307626, RN3, Rn3, RNASE3L, RNASEN, Rnasen, zgc:158612Protein level used designations for DROSHA
- drosha
- ribonuclease 3
- Ribonuclease 3
- RNase III
- drosha, double-stranded RNA-specific endoribonuclease
- nuclear RNase III Drosha
- p241
- protein Drosha
- putative protein p241 which interacts with transcription factor Sp1
- putative ribonuclease III
- ribonuclease III, nuclear
- ribonuclease type III, nuclear
- ethanol induced 2
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