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DRAP1 Proteins

(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].

recommended

DRAP1 Protein (AA 1-205) (GST tag) (ABIN1352006)

DRAP1 Origin: Human Host: Wheat germ Recombinant ELISA, AA, AP, WB

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recommended

DRAP1 Protein (AA 2-105) (GST tag) (ABIN1352008)

DRAP1 Origin: Human Host: Wheat germ Recombinant ELISA, AA, AP, WB

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recommended

DRAP1 Protein (AA 4-198, partial) (GST tag) (ABIN1046948)

DRAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA

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DRAP1 Proteins by Origin

Find DRAP1 Proteins for a variety of species such as anti-Human DRAP1, anti-Cow DRAP1, anti-Rat DRAP1. The species listed below are among those available. Click on a link to go to the corresponding products.

DRAP1 Proteins by Source

Here you will find DRAP1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DRAP1 Proteins by Protein Type

Here you can find DRAP1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

DRAP1 Proteins by Application

Find DRAP1 Proteins validated for a specific application such as ELISA, AP, AA, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DRAP1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

DRAP1 Protein (AA 1-205) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1352006

Quantity 10 μg

Datasheet Datasheet

DRAP1 Protein (AA 2-105) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1352008

Quantity 10 μg

Datasheet Datasheet

DRAP1 Protein (AA 4-198, partial) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1046948

Quantity 100 μg

Datasheet Datasheet

DRAP1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719758

Quantity 20 μg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475249

Quantity 1 mg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1625796

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our DRAP1 Proteins

Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

Klejman, Pereira, van Zeeburg, Gilfillan, Meisterernst, Timmers: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Goppelt, Stelzer, Lottspeich, Meisterernst: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).

Mermelstein, Yeung, Cao, Inostroza, Erdjument-Bromage, Eagelson, Landsman, Levitt, Tempst, Reinberg: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).

Aliases for DRAP1 Proteins

DR1-associated protein 1 (negative cofactor 2 alpha) (drap1) Proteins
DR1 associated protein 1 (DRAP1) Proteins
Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1) Proteins
Dr1 associated protein 1 (Drap1) Proteins
2310074H19Rik Proteins
DRAP1 Proteins
fb26e10 Proteins
NC2-alpha Proteins
wu:fb26e10 Proteins
zgc:56003 Proteins
zgc:77337 Proteins

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DRAP1 Proteins by Origin

DRAP1 Proteins by Source

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DRAP1 Proteins by Application

Popular DRAP1 Proteins

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Aliases for DRAP1 Proteins

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