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Dopamine Receptor D4 Products

(Dopamine Receptor D4 (DRD4))
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats\; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008].

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Featured Dopamine Receptor D4 Categories

Dopamine Receptor D4 Antibodies

High quality antibodies with extensive validation data.

Dopamine Receptor D4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Dopamine Receptor D4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Dopamine Receptor D4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (1)
  • (3)
Cat. No. ABIN652706
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257148
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN1679595
Quantity 100 μg
Datasheet Datasheet

Recommended Dopamine Receptor D4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966419
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955449
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN512481
Quantity 96 tests
Datasheet Datasheet

Recommended Dopamine Receptor D4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411477
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
Cat. No. ABIN7538217
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3134352
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Dopamine Receptor D4 products

Unland, Kerl, Schlosser, Farwick, Plagemann, Lechtape, Clifford, Kreth, Gerss, Mühlisch, Richter, Hasselblatt, Frühwald: "Epigenetic repression of the dopamine receptor D4 in pediatric tumors of the central nervous system." in: Journal of neuro-oncology, Vol. 116, Issue 2, pp. 237-49, (2014) (PubMed).

Chen, Hong, Chen, Fan, Zhang, Zhang, Zhu: "Distinctive expression and cellular distribution of dopamine receptors in the pancreatic islets of rats." in: Cell and tissue research, Vol. 357, Issue 3, pp. 597-606, (2014) (PubMed).

Kim, Seo, Sung, Kim: "Arsenic exposure in drinking water alters the dopamine system in the brains of C57BL/6 mice." in: Biological trace element research, Vol. 162, Issue 1-3, pp. 175-80, (2014) (PubMed).

Ma, Thapa, Morris, Michalakis, Biel, Frank, Bebak, Ding: "Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study." in: Human molecular genetics, Vol. 22, Issue 19, pp. 3906-19, (2013) (PubMed).

Zeng, Ye, Lu, Chua, Tan, Zhong: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." in: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).

Lai, Zhu, Huo, Sun, Yu, Wang, Chai, Li: "Association study of polymorphisms in the promoter region of DRD4 with schizophrenia, depression, and heroin addiction." in: Brain research, Vol. 1359, pp. 227-32, (2010) (PubMed).

Gadow, Devincent, Olvet, Pisarevskaya, Hatchwell: "Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder." in: The European journal of neuroscience, Vol. 32, Issue 6, pp. 1058-65, (2010) (PubMed).

Li, Sham, Owen, He: "Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD)." in: Human molecular genetics, Vol. 15, Issue 14, pp. 2276-84, (2006) (PubMed).

Chio, Drong, Riley, Gill, Slightom, Huff: "D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11813-9, (1994) (PubMed).

Synonyms and alternative names related to Dopamine Receptor D4

dopamine receptor D4 related sequence (drd4-rs), dopamine receptor D4 (DRD4), dopamine receptor D4 (Drd4), dopamine receptor D4 (SRU_2808), dopamine receptor D4 (MSMEG_3522), dopamine receptor D4b (drd4b), AW125663, D4DR, D4R, D4RA, Drd-4, DRD4, Drd4b, Drd4c, si:ch211-69h5.1, zgc:123021

Protein level used designations for Dopamine Receptor D4

  • dopamine D4b receptor
  • D(2C) dopamine receptor
  • D(4) dopamine receptor
  • dopamine D4 receptor
  • seven transmembrane helix receptor
  • d(2C) dopamine receptor
  • dopamine receptor 4
  • dopamine receptor D4
  • dopamine D4c receptor
  • dopamine receptor D4b
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