DOK4 Products
(Docking Protein 4 (DOK4))
Categories
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
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Featured DOK4 Categories
DOK4 Antibodies
High quality antibodies with extensive validation data.
DOK4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DOK4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN3020722
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6257147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN392073
Quantity
400 μL
Datasheet
Datasheet
Recommended DOK4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6203921
Quantity
96 tests
Datasheet
Datasheet
Recommended DOK4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351905
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2128954
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079112
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DOK4 products
: "Dok-4 is a novel negative regulator of T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7681-9, (2009) (PubMed).: "SRC family kinase activity is up-regulated in hormone-refractory prostate cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 10, pp. 3540-9, (2009) (PubMed).
: "DOK4 and DOK5: new Dok-related genes expressed in human T cells." in: Genes and immunity, Vol. 4, Issue 1, pp. 40-5, (2003) (PubMed).
: "Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 25323-30, (2003) (PubMed).
Synonyms and alternative names related to DOK4
docking protein 4 (DOK4), docking protein 4 (Dok4), DOK4Protein level used designations for DOK4
- IRS-5
- IRS5
- downstream of tyrosine kinase 4
- insulin receptor substrate 5
- docking protein 4
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