DOK2 Products
(DOK2)
Categories
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008].
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Featured DOK2 Categories
DOK2 Antibodies
High quality antibodies with extensive validation data.
DOK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
DOK2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DOK2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7150566
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN684148
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN392072
Quantity
400 μL
Datasheet
Datasheet
Recommended DOK2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380557
Quantity
2 x 96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593715
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1130515
Quantity
96 tests
Datasheet
Datasheet
Recommended DOK2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351902
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3078950
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3132011
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DOK2 products
: "Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 143-51, (2006) (PubMed).: "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).
: "Characterization of a novel member of the DOK family that binds and modulates Abl signaling." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8314-25, (2000) (PubMed).
: "Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses." in: The Journal of cell biology, Vol. 149, Issue 7, pp. 1419-32, (2000) (PubMed).
: "Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 4827-30, (1998) (PubMed).
: "The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R." in: Oncogene, Vol. 17, Issue 9, pp. 1097-108, (1998) (PubMed).
: "FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation." in: Immunity, Vol. 9, Issue 1, pp. 13-24, (1998) (PubMed).
Synonyms and alternative names related to DOK2
docking protein 2 (DOK2), docking protein 2 (Dok2), Dok-2, DokR, Frip, p56DOK, p56dok-2Protein level used designations for DOK2
- IL-Four Receptor Interacting Protein
- IL-four receptor-interacting protein
- dok-R
- dok-related protein
- downstream of tyrosine kinase 2
- p56 dok-2
- p56(dok-2)
- docking protein 2
- Downstream of tyrosine kinase 2
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