DOCK3 Products
(Dedicator of Cytokinesis 3 (DOCK3))
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This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement. [provided by RefSeq, Aug 2010].
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Featured DOCK3 Categories
DOCK3 Antibodies
High quality antibodies with extensive validation data.
DOCK3 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended DOCK3 Antibodies
Recommended DOCK3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955298
Quantity
96 tests
Datasheet
Datasheet
Recommended DOCK3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398815
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN6378923
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to DOCK3
dedicator of cytokinesis 3 (DOCK3), similar to dedicator of cytokinesis 3 (LOC561387), dedicator of cytokinesis 3 (dock3), dedicator of cytokinesis protein 3 (LOC100474164), dedicator of cyto-kinesis 3 (Dock3), mKIAA0299, MOCA, PBPProtein level used designations for DOCK3
- dedicator of cytokinesis 3
- similar to dedicator of cytokinesis 3
- dedicator of cytokinesis protein 3-like
- dedicator of cytokinesis protein 3
- modifier of cell adhesion
- presenilin-binding protein
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