DNMT3L Products
(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
Categories
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].
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Featured DNMT3L Categories
DNMT3L Antibodies
High quality antibodies with extensive validation data.
DNMT3L ELISA Kits
Reliable ELISA kits for a wide range of species.
DNMT3L Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DNMT3L Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
Cat. No.
ABIN5542515
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
Cat. No.
ABIN526180
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, IP, ChIP, ICC
Validations
- (4)
Cat. No.
ABIN6261345
Quantity
100 μL
Datasheet
Datasheet
Recommended DNMT3L ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960699
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN4993275
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative
Validations
Cat. No.
ABIN2947075
Quantity
96 tests
Datasheet
Datasheet
Recommended DNMT3L Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122681
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122680
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351873
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our DNMT3L products
: "Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands." in: BMC genomics, Vol. 16, pp. 517, (2016) (PubMed).: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).
: "DNA methyl transferases are differentially expressed in the human anterior eye segment." in: Acta ophthalmologica, Vol. 92, Issue 5, pp. e366-71, (2014) (PubMed).
: "An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism." in: PLoS ONE, Vol. 8, Issue 4, pp. e61758, (2013) (PubMed).
: "Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation." in: The EMBO journal, Vol. 26, Issue 8, pp. 2052-60, (2007) (PubMed).
: "Dnmt3L is a transcriptional repressor that recruits histone deacetylase." in: Nucleic acids research, Vol. 30, Issue 17, pp. 3831-8, (2002) (PubMed).
: "The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16916-21, (2002) (PubMed).
: "Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths." in: Molecular reproduction and development, Vol. 63, Issue 3, pp. 269-72, (2002) (PubMed).
: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ..." in: Nature, Vol. 420, Issue 6915, pp. 563-73, (2002) (PubMed).
: "Isolation and initial characterization of the mouse Dnmt3l gene." in: Cytogenetics and cell genetics, Vol. 92, Issue 1-2, pp. 122-6, (2001) (PubMed).
Synonyms and alternative names related to DNMT3L
DNA methyltransferase 3 like (DNMT3L), DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), DNA methyltransferase 3 like (Dnmt3l), D6Ertd14e, DNMT3L, ecat7Protein level used designations for DNMT3L
- DNA (cytosine-5-)-methyltransferase 3-like
- cytosine-5-methyltransferase 3-like protein
- DNA (cytosine-5)-methyltransferase 3-like
- human cytosine-5-methyltransferase 3-like protein
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