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DNMT1 Products

(DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

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DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

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Featured DNMT1 Categories

DNMT1 Antibodies

High quality antibodies with extensive validation data.

DNMT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DNMT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DNMT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IF
Validations
  • (3)
  • (9)
Cat. No. ABIN6139745
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (5)
Cat. No. ABIN1724879
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
Cat. No. ABIN7259344
Quantity 200 μL
Datasheet Datasheet

Recommended DNMT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966396
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962646
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955419
Quantity 96 tests
Datasheet Datasheet

Recommended DNMT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351865
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN2719616
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505354
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DNMT1 products

Huang, Chou, Li, Shih, Lin, Chuang, Chiou, Su, Harn: "Epigenetic targeting DNMT1 of pancreatic ductal adenocarcinoma using interstitial control release biodegrading polymer reduced tumor growth through hedgehog pathway inhibition." in: Pharmacological research, Vol. 139, pp. 50-61, (2019) (PubMed).

Gatta, Grayson, Auta, Saudagar, Dong, Chen, Krishnan, Drnevich, Pandey, Guidotti: "Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1)." in: Molecular psychiatry, (2019) (PubMed).

Fisslthaler, Zippel, Abdel Malik, Delgado Lagos, Zukunft, Thoele, Siuda, Soehnlein, Wittig, Heidler, Weigert, Fleming: "Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis." in: International journal of molecular sciences, Vol. 20, Issue 12, (2019) (PubMed).

Liberti, Zepp, Bartoni, Liberti, Zhou, Lu, Morley, Morrisey: "Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate." in: Developmental biology, (2019) (PubMed).

Kuo, Wu, Li, Yang, Kong: "Anthocyanin Delphinidin Prevents Neoplastic Transformation of Mouse Skin JB6 P+ Cells: Epigenetic Re-activation of Nrf2-ARE Pathway." in: The AAPS journal, Vol. 21, Issue 5, pp. 83, (2019) (PubMed).

Sun, Cui, Feng, Liu, Liu: "TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity." in: The Journal of experimental medicine, Vol. 216, Issue 12, pp. 2819-2837, (2019) (PubMed).

Chu, Ko, Wang, Lin, Wang, Lin, Wu, Wang, Wang: "Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia." in: Cell death & disease, Vol. 8, Issue 11, pp. e3167, (2018) (PubMed).

Li, Su, Guo, Zhang, Wu, Gao, Zheng, Du, Zhang, Kong: "Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells." in: Chemical research in toxicology, Vol. 31, Issue 2, pp. 88-96, (2018) (PubMed).

Yang, Wu, Li, Gao, Yang, Li, Kong: "The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells." in: Molecular carcinogenesis, (2018) (PubMed).

Meliso, Micali, Silva, Sabedot, Coetzee, Koch, Fahlbusch, Noushmehr, Schneider-Stock, Jasiulionis: "SIRT1 regulates Mxd1 during malignant melanoma progression." in: Oncotarget, Vol. 8, Issue 70, pp. 114540-114553, (2018) (PubMed).

Synonyms and alternative names related to DNMT1

DNA methyltransferase 1 (DNMT1), DNA (cytosine-5-)-methyltransferase 1 (dnmt1), DNA methyltransferase 1 (Dnmt1), methyltransferase 1 (MET1), DNA methyltransferase (cytosine-5) 1 (Dnmt1), ADCADN, AIM, cb983, cb1075, CXXC9, Cxxc9, DDM2, DECREASED DNA METHYLATION 2, dmnt1, DMT01, DMT1, DNA METHYLTRANSFERASE, DNA METHYLTRANSFERASE 01, DNA METHYLTRANSFERASE 1, DNMT, Dnmt, Dnmt1o, fb05h01, HSN1E, m.MmuI, MCMT, Met-1, Met1, MET2, methyltransferase 1, METHYLTRANSFERASE 2, METHYLTRANSFERASE I, METI, MommeD2, mta, MTase, wu:fb05h01

Protein level used designations for DNMT1

  • DNA (cytosine-5)-methyltransferase 1
  • ddn
  • CXXC-type zinc finger protein 9
  • DNA MTase HsaI
  • DNA methyltransferase HsaI
  • m.HsaI
  • DNA methyltransferase 1
  • DNA (cytosine 5 ) methyltransferase 1
  • DNA methyltransferase (cytosine 5 ) methyltransferase
  • DNA methyltransferase b
  • DNA MTase RnoIP
  • DNA methyltransferase (cytosine-5) 1
  • DNA methyltransferase I
  • MCMT
  • m.RnoIP
  • DNA MTase GgaI
  • DNA MeTase
  • DNA methyltransferase GgaI
  • m.GgaI
  • DNA MTase MmuI
  • DNA methyltransferase MmuI
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