DNM2 Products
(Dynamin 2 (DNM2))
Categories
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010].
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Featured DNM2 Categories
DNM2 Antibodies
High quality antibodies with extensive validation data.
DNM2 ELISA Kits
Reliable ELISA kits for a wide range of species.
DNM2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DNM2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity
Human
Application
WB, IHC, IP, ICC
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- (8)
Cat. No.
ABIN7433204
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS, Neut
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- (5)
Cat. No.
ABIN5611153
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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- (3)
Cat. No.
ABIN7127459
Quantity
100 μL
Datasheet
Datasheet
Recommended DNM2 ELISA Kits
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6966433
Quantity
96 tests
Datasheet
Datasheet
Reactivity
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Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955474
Quantity
96 tests
Datasheet
Datasheet
Reactivity
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Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN770727
Quantity
96 tests
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Datasheet
Recommended DNM2 Proteins
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Cat. No.
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Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351857
Quantity
10 μg
Datasheet
Datasheet
Reactivity
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Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351859
Quantity
10 μg
Datasheet
Datasheet
Reactivity
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Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7393319
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DNM2 products
: "Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes." in: The Journal of cell biology, Vol. 218, Issue 11, pp. 3647-3662, (2019) (PubMed).: "PACSIN2-dependent apical endocytosis regulates the morphology of epithelial microvilli." in: Molecular biology of the cell, Vol. 30, Issue 19, pp. 2515-2526, (2019) (PubMed).
: "Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 389, Issue 11, pp. 1171-1182, (2016) (PubMed).
: "Dynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics." in: The Journal of biological chemistry, Vol. 289, Issue 35, pp. 24383-96, (2014) (PubMed).
: "Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis." in: Journal of virology, (2013) (PubMed).
: "Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells." in: The Journal of biological chemistry, Vol. 287, Issue 34, pp. 28932-42, (2012) (PubMed).
: "Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules." in: Journal of virology, Vol. 86, Issue 24, pp. 13653-61, (2012) (PubMed).
: "Cell entry of avian reovirus follows a caveolin-1-mediated and dynamin-2-dependent endocytic pathway that requires activation of p38 mitogen-activated protein kinase (MAPK) and Src signaling pathways ..." in: The Journal of biological chemistry, Vol. 286, Issue 35, pp. 30780-94, (2011) (PubMed).
: "Dynamin is functionally coupled to insulin granule exocytosis." in: The Journal of biological chemistry, Vol. 282, Issue 46, pp. 33530-6, (2007) (PubMed).
: "Rapid purification of native dynamin I and colorimetric GTPase assay." in: Methods in enzymology, Vol. 404, pp. 556-69, (2006) (PubMed).
Synonyms and alternative names related to DNM2
dynamin 2 (DNM2), dynamin 2 (dnm2), dynamin 2 L homeolog (dnm2.L), dynamin 2 (Dnm2), dynamin 2a (dnm2a), dynamin 2-like (DNM2L), CMT2M, cmtdi1, CMTDI1, cmtdib, CMTDIB, DI-CMTB, dnm2, DYIIAAB, dyn2, DYN2, Dyn2, dynamin-2, dynII, DYNII, LCCS5, Udnm, zgc:114072Protein level used designations for DNM2
- dynamin-2
- dynamin 2
- dynamin-2-like
- dynamin II
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