DNASE2 Products
(Deoxyribonuclease II, Lysosomal (DNASE2))
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This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008].
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Featured DNASE2 Categories
DNASE2 Antibodies
High quality antibodies with extensive validation data.
DNASE2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DNASE2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IF (cc), IF (p), IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN872658
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7149730
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (2)
Cat. No.
ABIN560629
Quantity
50 μL
Datasheet
Datasheet
Recommended DNASE2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966330
Quantity
96 tests
Datasheet
Datasheet
Recommended DNASE2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351846
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351844
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719398
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our DNASE2 products
: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).
: "Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1216-9, (1998) (PubMed).
: "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family." in: Cell, Vol. 85, Issue 6, pp. 829-39, (1996) (PubMed).
Synonyms and alternative names related to DNASE2
Deoxyribonuclease II (DNaseII), deoxyribonuclease II, lysosomal L homeolog (dnase2.L), deoxyribonuclease 2, lysosomal (DNASE2), deoxyribonuclease II, lysosomal (dnase2), deoxyribonuclease II (dnase2), deoxyribonuclease II alpha (Dnase2a), deoxyribonuclease 2, lysosomal (Dnase2), CG7780, DDBDRAFT_0188966, DDBDRAFT_0252883, DDB_0188966, DDB_0252883, dDNase II, Dmel\\CG7780, DNase, DNase-1, DNase 1, DNase1, dnase2, DNASE2, Dnase2, DNASE2A, Dnase2a, DNL, DNL2, fa92d01, LOC733868, MGC80103, wu:fa56d08, wu:fa92d01Protein level used designations for DNASE2
- deoxyribonuclease II
- CG7780-PA
- DNaseII-PA
- acid DNase
- deoxyribonuclease 1
- deoxyribonuclease II, lysosomal
- deoxyribonuclease-2-alpha
- fa56d08
- DNase II alpha
- lysosomal DNase II
- DNase II, lysosomal
- R31240_2
- deoxyribonuclease II alpha
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