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DNASE2 Products

(Deoxyribonuclease II, Lysosomal (DNASE2))

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This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008].

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Featured DNASE2 Categories

DNASE2 Antibodies

High quality antibodies with extensive validation data.

DNASE2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DNASE2 Antibodies

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Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity Human, Mouse
Application ELISA, IF (cc), IF (p), IHC (p)
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Cat. No. ABIN872658
Quantity 100 μL
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Reactivity Human
Application ELISA, WB, IHC
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  • (2)
Cat. No. ABIN7149730
Quantity 100 μg
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Reactivity Human
Application ELISA, WB
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Cat. No. ABIN560629
Quantity 50 μL
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Recommended DNASE2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
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Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6966330
Quantity 96 tests
Datasheet Datasheet

Recommended DNASE2 Proteins

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Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Wheat germ
Validations
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Cat. No. ABIN1351846
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1351844
Quantity 10 μg
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Reactivity Human
Source HEK-293 Cells
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Cat. No. ABIN2719398
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our DNASE2 products

Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

Yu, Peters, King, Page, Hieter, Kirschner: "Identification of a cullin homology region in a subunit of the anaphase-promoting complex." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1219-22, (1998) (PubMed).

Zachariae, Shevchenko, Andrews, Ciosk, Galova, Stark, Mann, Nasmyth: "Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins." in: Science (New York, N.Y.), Vol. 279, Issue 5354, pp. 1216-9, (1998) (PubMed).

Kipreos, Lander, Wing, He, Hedgecock: "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family." in: Cell, Vol. 85, Issue 6, pp. 829-39, (1996) (PubMed).

Synonyms and alternative names related to DNASE2

Deoxyribonuclease II (DNaseII), deoxyribonuclease II, lysosomal L homeolog (dnase2.L), deoxyribonuclease 2, lysosomal (DNASE2), deoxyribonuclease II, lysosomal (dnase2), deoxyribonuclease II (dnase2), deoxyribonuclease II alpha (Dnase2a), deoxyribonuclease 2, lysosomal (Dnase2), CG7780, DDBDRAFT_0188966, DDBDRAFT_0252883, DDB_0188966, DDB_0252883, dDNase II, Dmel\\CG7780, DNase, DNase-1, DNase 1, DNase1, dnase2, DNASE2, Dnase2, DNASE2A, Dnase2a, DNL, DNL2, fa92d01, LOC733868, MGC80103, wu:fa56d08, wu:fa92d01

Protein level used designations for DNASE2

  • deoxyribonuclease II
  • CG7780-PA
  • DNaseII-PA
  • acid DNase
  • deoxyribonuclease 1
  • deoxyribonuclease II, lysosomal
  • deoxyribonuclease-2-alpha
  • fa56d08
  • DNase II alpha
  • lysosomal DNase II
  • DNase II, lysosomal
  • R31240_2
  • deoxyribonuclease II alpha
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