DMPK Products
(Dystrophia Myotonica-Protein Kinase (DMPK))
Categories
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Featured DMPK Categories
DMPK Antibodies
High quality antibodies with extensive validation data.
DMPK ELISA Kits
Reliable ELISA kits for a wide range of species.
DMPK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DMPK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7073790
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (5)
Cat. No.
ABIN950119
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN515032
Quantity
100 μg
Datasheet
Datasheet
Recommended DMPK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648192
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1143793
Quantity
96 tests
Datasheet
Datasheet
Recommended DMPK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351723
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN5508895
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7423321
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DMPK products
: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." in: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).: "Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal reorganization and apoptotic-like blebbing in lens cells." in: Cell motility and the cytoskeleton, Vol. 45, Issue 2, pp. 133-48, (2000) (PubMed).
: "Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies." in: Human molecular genetics, Vol. 7, Issue 12, pp. 1957-65, (1998) (PubMed).
: "Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene." in: Human molecular genetics, Vol. 2, Issue 3, pp. 299-304, (1993) (PubMed).
Synonyms and alternative names related to DMPK
DM1 protein kinase (DMPK), dystrophia myotonica-protein kinase (Dmpk), DM1 protein kinase (Dmpk), DM, DM1, DM1PK, Dm15, DMK, DMPK, MDPK, MT-PKProtein level used designations for DMPK
- dystrophia myotonica-protein kinase
- myotonic dystrophy protein kinase
- myotonin-protein kinase-like
- DM protein kinase
- DM-kinase
- DM1 protein kinase
- myotonic dystrophy associated protein kinase
- myotonin protein kinase A
- myotonin-protein kinase
- thymopoietin homolog
- dystrophia myotonica kinase, B15
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