DMP1 Products
(Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
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Featured DMP1 Categories
DMP1 Antibodies
High quality antibodies with extensive validation data.
DMP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DMP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DMP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN515028
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (3)
Cat. No.
ABIN564296
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN2775903
Quantity
100 μL
Datasheet
Datasheet
Recommended DMP1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889432
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1979445
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2708499
Quantity
96 tests
Datasheet
Datasheet
Recommended DMP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351721
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351737
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318398
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our DMP1 products
: "LncRNA H19 promotes the committed differentiation of stem cells from apical papilla via miR-141/SPAG9 pathway." in: Cell death & disease, Vol. 10, Issue 2, pp. 130, (2019) (PubMed).: "The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).
: "Oestrogen receptor α regulates the odonto/osteogenic differentiation of stem cells from apical papilla via ERK and JNK MAPK pathways." in: Cell proliferation, Vol. 51, Issue 6, pp. e12485, (2018) (PubMed).
: "Mineral trioxide aggregate enhances the osteogenic capacity of periodontal ligament stem cells via NF-κB and MAPK signaling pathways." in: Journal of cellular physiology, Vol. 233, Issue 3, pp. 2386-2397, (2017) (PubMed).
: "Tooth Germ-Like Construct Transplantation for Whole-Tooth Regeneration: An In Vivo Study in the Miniature Pig." in: Artificial organs, Vol. 40, Issue 4, pp. E39-50, (2016) (PubMed).
: "Eckols reduce dental pulp inflammation through the ERK1/2 pathway independent of COX-2 inhibition." in: Oral diseases, Vol. 20, Issue 8, pp. 827-32, (2014) (PubMed).
: "Effects of canonical NF-κB signaling pathway on the proliferation and odonto/osteogenic differentiation of human stem cells from apical papilla." in: BioMed research international, Vol. 2014, pp. 319651, (2014) (PubMed).
: "Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence." in: Cellular signalling, Vol. 25, Issue 12, pp. 2540-7, (2013) (PubMed).
: "KLF4 Promotes the Odontoblastic Differentiation of Human Dental Pulp Cells." in: Journal of endodontics, Vol. 37, Issue 7, pp. 948-54, (2011) (PubMed).
: "The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias." in: Leukemia, Vol. 22, Issue 5, pp. 1087-90, (2008) (PubMed).
Synonyms and alternative names related to DMP1
cyclin D binding myb like transcription factor 1 (DMTF1), cyclin D binding myb-like transcription factor 1 (Dmtf1), cyclin D binding myb like transcription factor 1 (dmtf1), cyclin D binding myb-like transcription factor 1 (dmtf1), cyclin D binding myb like transcription factor 1 (Dmtf1), Dimp, DMP1, Dmp1, DMTF, DMTF1, hDMP1, zgc:92448Protein level used designations for DMP1
- cyclin D-binding Myb-like protein
- cyclin-D-binding Myb-like transcription factor 1
- cyclin-D-interacting Myb-like protein 1
- hDMTF1
- D-interacting myb-like protein
- cyclin D binding myb-like transcription factor 1D-interacting myb-like protein
- mDmp1
- cyclin D binding myb-like transcription factor 1
- cyclin-D-binding Myb-like transcription factor 1-like
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