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DLK1 Products

(delta-Like 1 Homolog (Drosophila) (DLK1))

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This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].

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Featured DLK1 Categories

DLK1 Antibodies

High quality antibodies with extensive validation data.

DLK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DLK1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DLK1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (2)
  • (4)
Cat. No. ABIN969086
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat, Sheep
Application WB, ELISA, FACS, IF (p), IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN740055
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN6243159
Quantity 400 μL
Datasheet Datasheet

Recommended DLK1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6974778
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966313
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6961981
Quantity 96 tests
Datasheet Datasheet

Recommended DLK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274477
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274479
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274478
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DLK1 products

Carr, Toma, Johnston, Steadman, Yuzwa, Mahmud, Frankland, Kaplan, Miller: "Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration." in: Cell stem cell, Vol. 24, Issue 2, pp. 240-256.e9, (2019) (PubMed).

Hu, Guan, Liu, Dai, Tang, Xiao, Qian, Sharrow, Ye, Wu, Xu: "Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells." in: Stem cell reports, Vol. 9, Issue 2, pp. 464-477, (2018) (PubMed).

Peng, Jia, Li, Xie, Xie, Zheng: "Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes." in: Biomedical and environmental sciences : BES, Vol. 31, Issue 7, pp. 507-514, (2018) (PubMed).

Kilian, Beck-Sickinger: "Recombinant expression and characterization of biologically active protein delta homolog 1." in: Protein expression and purification, Vol. 110, pp. 72-8, (2015) (PubMed).

Kessler, Laggai, Barghash, Schultheiss, Lederer, Artl, Helms, Haybaeck, Kiemer: "IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype." in: Cell death & disease, Vol. 6, pp. e1894, (2015) (PubMed).

Schrey, Wurst, Ebert, Kralisch, Drewlo, Stepan, Lössner, Platz, Kratzsch, Stumvoll, Fasshauer: "The adipokine preadipocyte factor-1 is downregulated in preeclampsia and expressed in placenta." in: Cytokine, Vol. 75, Issue 2, pp. 338-43, (2015) (PubMed).

Kluth, Radke, Kögler: "Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1." in: Stem cells international, Vol. 2013, pp. 985285, (2013) (PubMed).

Kang, Liu, Guan, Wang, Gong, Yang, Yan, Wang, Fu, Cao, Xiao: "Effects of co-culturing BMSCs and auricular chondrocytes on the elastic modulus and hypertrophy of tissue engineered cartilage." in: Biomaterials, Vol. 33, Issue 18, pp. 4535-44, (2012) (PubMed).

Rodríguez, Higueras, González-Rajal, Alfranca, Fierro-Fernández, García-Fernández, Ruiz-Hidalgo, Monsalve, Rodríguez-Pascual, Redondo, de la Pompa, Laborda, Lamas: "The non-canonical NOTCH ligand DLK1 exhibits a novel vascular role as a strong inhibitor of angiogenesis." in: Cardiovascular research, Vol. 93, Issue 2, pp. 232-41, (2012) (PubMed).

Zhou, Wang, Wang, Zhu, Shu, Liao, Yu, Gao, Xi, Wang, Zhang, Yuan, Jiang: "Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray." in: Meat science, Vol. 86, Issue 2, pp. 440-50, (2010) (PubMed).

Synonyms and alternative names related to DLK1

delta like canonical Notch ligand 1 (DLL1), delta like non-canonical Notch ligand 1 (DLK1), delta like canonical Notch ligand 1 (Dll1), delta-like 1 homolog (Drosophila) (DLK1), delta-like 1 (Drosophila) (Dll1), delta-like 1 homolog (Drosophila) (Dlk1), delta like non-canonical Notch ligand 1 (Dlk1), AW742678, Delta, DELTA1, Delta1, DL1, DLK, DLK-1, DlkI, FA1, Ly107, Peg9, pG2, Pref-1, pref-1, PREF1, SCP1, ZOG, Zog

Protein level used designations for DLK1

  • H-Delta-1
  • delta-like protein 1
  • drosophila Delta homolog 1
  • fetal antigen 1
  • preadipocyte factor 1
  • protein delta homolog 1
  • secredeltin
  • delta1
  • delta-like homolog
  • preadipocyte factor-1
  • delta-like 1 homolog (Drosophila)
  • protein delta homolog 1-like
  • delta like-1
  • adipocyte differentiation inhibitor protein
  • stromal cell derived protein 1
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