DLC1 Products
(Deleted in Liver Cancer 1 (DLC1))
Categories
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010].
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Featured DLC1 Categories
DLC1 Antibodies
High quality antibodies with extensive validation data.
DLC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended DLC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
IHC, ELISA, IF
Validations
- (1)
- (5)
Cat. No.
ABIN185264
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6261308
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856359
Quantity
100 μL
Datasheet
Datasheet
Recommended DLC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955333
Quantity
96 tests
Datasheet
Datasheet
Recommended DLC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137440
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DLC1 products
: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." in: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).: "Identification of StARD3 as a lutein-binding protein in the macula of the primate retina." in: Biochemistry, Vol. 50, Issue 13, pp. 2541-9, (2011) (PubMed).
: "Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 30, Issue 1, pp. 139-48, (2009) (PubMed).
: "Sequence variants of DLC1 in colorectal and ovarian tumours." in: Human mutation, Vol. 15, Issue 2, pp. 156-65, (2000) (PubMed).
: "Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho." in: The Journal of biological chemistry, Vol. 274, Issue 25, pp. 17757-62, (1999) (PubMed).
: "Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP." in: Cancer research, Vol. 58, Issue 10, pp. 2196-9, (1998) (PubMed).
: "A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities." in: The EMBO journal, Vol. 14, Issue 2, pp. 286-91, (1995) (PubMed).
Synonyms and alternative names related to DLC1
DLC1 Rho GTPase activating protein (DLC1), DLC1 Rho GTPase activating protein S homeolog (dlc1.S), DLC1 Rho GTPase activating protein (dlc1), rho GTPase-activating protein 7 (LOC100456847), deleted in liver cancer 1 (Dlc1), DLC1 Rho GTPase activating protein (Dlc1), rho GTPase-activating protein 7 (LOC100729904), A730069N07Rik, ARHGAP7, Arhgap7, DLC-1, Dlc-1, dlc-1, Dlc1, HP, p122-RhoGAP, RhoGAP, rhogap7, STARD12, StARD12Protein level used designations for DLC1
- Rho-GTPase-activating protein 7
- START domain-containing protein 12
- StAR-related lipid transfer (START) domain containing 12
- deleted in liver cancer 1 protein
- deleted in liver cancer 1 variant 2
- rho GTPase-activating protein 7
- rho-type GTPase-activating protein 7
- deleted in liver cancer 1
- deleted in liver cancer 1 protein homolog
- stAR-related lipid transfer protein 12
- rho GTPase-activating protein 7-like
- Deleted in liver cancer 1 protein homolog
- Rho-type GTPase-activating protein 7
- p122-RhoGAP
- dlc-1
- rho GTPase activating protein 7
- stARD12
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