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DLAT Proteins

(Dihydrolipoyl Transacetylase (DLAT))
This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009].
DLAT Protein (AA 169-273) (His-IF2DI Tag) DLAT Protein (AA 169-273) (His-IF2DI Tag) DLAT Protein (AA 169-273) (His-IF2DI Tag) (ABIN7122666)

DLAT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

DLAT Protein (AA 1-647) (GST tag) DLAT Protein (AA 1-647) (GST tag) DLAT Protein (AA 1-647) (GST tag) (ABIN1351656)

DLAT Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

DLAT Protein (AA 374-631) (His tag) (ABIN7403039)

DLAT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

DLAT Proteins by Origin

Find DLAT Proteins for a variety of species such as anti-Human DLAT, anti-Mouse DLAT, anti-Rat DLAT. The species listed below are among those available. Click on a link to go to the corresponding products.

DLAT Proteins by Source

Here you will find DLAT Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

DLAT Proteins by Protein Type

Here you can find DLAT Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

DLAT Proteins by Application

Find DLAT Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DLAT Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122666
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351656
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403039
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7391693
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5709403
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009179
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719517
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1475200
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1062608
Quantity 1 mg
Datasheet Datasheet

Aliases for DLAT Proteins

midline uncoordinated (muc) Proteins
dihydrolipoamide S-acetyltransferase L homeolog (dlat.L) Proteins
dihydrolipoamide S-acetyltransferase (DLAT) Proteins
dihydrolipoamide S-acetyltransferase (Dlat) Proteins
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat) Proteins
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat) Proteins
6332404G05Rik Proteins
anon-WO0118547.121 Proteins
DLAT Proteins
DLTA Proteins
Dmel\\CG5261 Proteins
EP(2)0816 Proteins
EP816 Proteins
PDC-E2 Proteins
PDCE2 Proteins
wu:fc14f10 Proteins
wu:fc21f08 Proteins
wu:fc86g11 Proteins
wu:fj57d06 Proteins
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