DIS3L Products
(DIS3-Like Exonuclease 1 (DIS3L))
Categories
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
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Featured DIS3L Categories
DIS3L Antibodies
High quality antibodies with extensive validation data.
DIS3L ELISA Kits
Reliable ELISA kits for a wide range of species.
DIS3L Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DIS3L Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7150013
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN530352
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN651802
Quantity
400 μL
Datasheet
Datasheet
Recommended DIS3L ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1129844
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1129845
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1129846
Quantity
96 tests
Datasheet
Datasheet
Recommended DIS3L Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351631
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092157
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136343
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DIS3L products
: "Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target." in: Nucleic acids research, Vol. 42, Issue 2, pp. 1270-90, (2014) (PubMed).: "Dis3-like 1: a novel exoribonuclease associated with the human exosome." in: The EMBO journal, Vol. 29, Issue 14, pp. 2358-67, (2010) (PubMed).
Synonyms and alternative names related to DIS3L
DIS3 like exosome 3'-5' exoribonuclease (DIS3L), DIS3 like exosome 3'-5' exoribonuclease (dis3l), DIS3 like exosome 3'-5' exoribonuclease (Dis3l), DIS3-like exosome 3'-5' exoribonuclease (Dis3l), DIS3 like exosome 3'-5' exoribonuclease (dis3l.L), AV340375, DIS3L1, RGD1308959, zgc:158615Protein level used designations for DIS3L
- DIS3-like exonuclease 1
- DIS3-like exonuclease 1-like
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