DIO1 Products
(Deiodinase, Iodothyronine, Type I (DIO1))
Categories
The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence. [provided by RefSeq, Jul 2008].
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Featured DIO1 Categories
DIO1 Antibodies
High quality antibodies with extensive validation data.
DIO1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DIO1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DIO1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ICC, IF
Validations
- (2)
Cat. No.
ABIN6261300
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN390946
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7236774
Quantity
200 μL
Datasheet
Datasheet
Recommended DIO1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955326
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966305
Quantity
96 tests
Datasheet
Datasheet
Recommended DIO1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351604
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351606
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7398731
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DIO1 products
: "Jinlida Granules Improve Dysfunction of Hypothalamic-Pituitary-Thyroid Axis in Diabetic Rats Induced by STZ." in: BioMed research international, Vol. 2018, pp. 4764030, (2019) (PubMed).: "Type of sweet flavour carrier affects thyroid axis activity in male rats." in: European journal of nutrition, (2017) (PubMed).
Synonyms and alternative names related to DIO1
iodothyronine deiodinase 1 (DIO1), type I iodothyronine deiodinase-like (LOC100231867), deiodinase, iodothyronine, type I (Dio1), deiodinase, iodothyronine type 1 L homeolog (dio1.L), iodothyronine deiodinase 1 (dio1), 5DI, cb685, D1, Deio1, DIOI, ITDI1, TXDI1, zgc:92323Protein level used designations for DIO1
- DIOI
- thyroxine deiodinase type I (selenoprotein)
- type 1 DI
- type I iodothyronine deiodinase
- type-I 5'-deiodinase
- thyroxine deiodinase, type I
- 5DI
- thyroxine deiodinase type 1
- Type 1 DI
- Type-I 5'-deiodinase
- deiodinase, iodothyronine, type I
- type 1 deiodinase
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