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Dihydropyrimidine Dehydrogenase Products

(Dihydropyrimidine Dehydrogenase (DPYD))
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

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Featured Dihydropyrimidine Dehydrogenase Categories

Dihydropyrimidine Dehydrogenase Antibodies

High quality antibodies with extensive validation data.

Dihydropyrimidine Dehydrogenase ELISA Kits

Reliable ELISA kits for a wide range of species.

Dihydropyrimidine Dehydrogenase Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Dihydropyrimidine Dehydrogenase Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN560640
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6261361
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN3187761
Quantity 100 μL
Datasheet Datasheet

Recommended Dihydropyrimidine Dehydrogenase ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955393
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955394
Quantity 96 tests
Datasheet Datasheet
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
Cat. No. ABIN1129485
Quantity 96 tests
Datasheet Datasheet

Recommended Dihydropyrimidine Dehydrogenase Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351981
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351979
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395647
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Dihydropyrimidine Dehydrogenase products

Kuilenburg, Meijer, Tanck, Dobritzsch, Zoetekouw, Dekkers, Roelofsen, Meinsma, Wymenga, Kulik, Büchel, Hennekam, Largiadèr: "Phenotypic and clinical implications of variants in the dihydropyrimidine dehydrogenase gene." in: Biochimica et biophysica acta, Vol. 1862, Issue 4, pp. 754-62, (2016) (PubMed).

Abuohashish, Ahmed, Al-Rejaie, Eltahir: "The antidepressant bupropion exerts alleviating properties in an ovariectomized osteoporotic rat model." in: Acta pharmacologica Sinica, Vol. 36, Issue 2, pp. 209-20, (2015) (PubMed).

Li, Dong, Zhao, Tang, Chen, Ding, Men, Luo, Du, Ge, Tan, Cao, Liu: "The upregulation of dihydropyrimidine dehydrogenase in liver is involved in acquired resistance to 5-fluorouracil." in: European journal of cancer (Oxford, England : 1990), Vol. 49, Issue 7, pp. 1752-60, (2013) (PubMed).

Abuohashish, Al-Rejaie, Al-Hosaini, Parmar, Ahmed: "Alleviating effects of morin against experimentally-induced diabetic osteopenia." in: Diabetology & metabolic syndrome, Vol. 5, Issue 1, pp. 5, (2013) (PubMed).

Synonyms and alternative names related to Dihydropyrimidine Dehydrogenase

dihydropyrimidine dehydrogenase (DPYD), dihydropyrimidine dehydrogenase (Dpyd), dihydropyrimidine dehydrogenase b (dpydb), dihydropyrimidine dehydrogenase L homeolog (dpyd.L), dihydropyrimidine dehydrogenase (EHI_012980), dihydropyrimidine dehydrogenase [NADP(+)] (LOC5573038), dihydropyrimidine dehydrogenase (EDI_044620), dihydropyrimidine dehydrogenase (pyd1), dihydropyrimidine dehydrogenase a, tandem duplicate 1 (dpyda.1), 14.t00017, AI315208, DDBDRAFT_0189681, DDBDRAFT_0231100, DDB_0189681, DDB_0231100, DHP, dhp, DHPDHASE, dhpdhase, DPD, dpd, DPYD, dpyd, dpyda, E330028L06Rik, zgc:77205, zgc:153505

Protein level used designations for Dihydropyrimidine Dehydrogenase

  • DHPDHase
  • DPD
  • dihydropyrimidine dehydrogenase [NADP(+)]
  • dihydrothymine dehydrogenase
  • dihydrouracil dehydrogenase
  • dihydropyrimidine dehydrogenase
  • uncharacterized protein LOC768165
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