DIAPH1 Products
(Diaphanous Homolog 1 (DIAPH1))
Categories
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured DIAPH1 Categories
DIAPH1 Antibodies
High quality antibodies with extensive validation data.
DIAPH1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DIAPH1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DIAPH1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), ICC
Validations
- (4)
Cat. No.
ABIN2855273
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN6263174
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN2855266
Quantity
100 μL
Datasheet
Datasheet
Recommended DIAPH1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955376
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5653657
Quantity
96 tests
Datasheet
Datasheet
Recommended DIAPH1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351590
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399667
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092158
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DIAPH1 products
: "Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex." in: Journal of cell science, Vol. 124, Issue Pt 18, pp. 3118-26, (2011) (PubMed).: "Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility." in: PLoS ONE, Vol. 6, Issue 8, pp. e23070, (2011) (PubMed).
: "Regulation of cell-cell adhesion by Abi/Diaphanous complexes." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1735-48, (2009) (PubMed).
: "Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor." in: Biology of reproduction, Vol. 76, Issue 6, pp. 971-82, (2007) (PubMed).
: "Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1." in: The Journal of experimental medicine, Vol. 204, Issue 9, pp. 2031-8, (2007) (PubMed).
: "Regulation of mitochondria distribution by RhoA and formins." in: Journal of cell science, Vol. 119, Issue Pt 4, pp. 659-70, (2006) (PubMed).
: "Chlamydial TARP is a bacterial nucleator of actin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 42, pp. 15599-604, (2006) (PubMed).
: "The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition." in: Current biology : CB, Vol. 13, Issue 15, pp. 1335-40, (2003) (PubMed).
: "The architecture of hearing." in: Science (New York, N.Y.), Vol. 278, Issue 5341, pp. 1223-4, (1997) (PubMed).
: "p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin." in: The EMBO journal, Vol. 16, Issue 11, pp. 3044-56, (1997) (PubMed).
Synonyms and alternative names related to DIAPH1
diaphanous related formin 1 (DIAPH1), diaphanous related formin 1 (diaph1), diaphanous related formin 2 (DIAPH2), diaphanous-related formin 1 (Diaph1), protein diaphanous homolog 1 (LOC100457442), diaphanous related formin 1 (Diaph1), D18Wsu154e, dfna1, DFNA1, dia1, Dia1, DIA1, diap1, Diap1, DIAPH1, Diaph1, DIAPH2, drf1, Drf1, DRF1, hDIA1, lfhl1, LFHL1, mKIAA4062, p140mDiaProtein level used designations for DIAPH1
- diaphanous homolog 1 (Drosophila)
- diaphanous homolog 1
- diaphanous homolog 2
- protein diaphanous homolog 1
- protein diaphanous homolog 1-like
- diaphanous-related formin-1
- mDIA1
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