DGCR8 Products
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Categories
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].
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Featured DGCR8 Categories
DGCR8 Antibodies
High quality antibodies with extensive validation data.
DGCR8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DGCR8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (4)
Cat. No.
ABIN527085
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IF
Validations
- (5)
Cat. No.
ABIN950085
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN527086
Quantity
100 μg
Datasheet
Datasheet
Recommended DGCR8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6203730
Quantity
96 tests
Datasheet
Datasheet
Recommended DGCR8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351506
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351505
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092171
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DGCR8 products
: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).: "Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 9, pp. 2113-22, (2013) (PubMed).
: "Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery." in: PLoS ONE, Vol. 7, Issue 7, pp. e40662, (2012) (PubMed).
: "Biogenesis of mammalian microRNAs by a non-canonical processing pathway." in: Nucleic acids research, Vol. 40, Issue 10, pp. 4626-40, (2012) (PubMed).
: "NMDA mediated contextual conditioning changes miRNA expression." in: PLoS ONE, Vol. 6, Issue 9, pp. e24682, (2011) (PubMed).
: "MicroRNAs are expressed and processed by human primary macrophages." in: Cellular immunology, Vol. 263, Issue 1, pp. 1-8, (2010) (PubMed).
: "Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis." in: The Journal of biological chemistry, Vol. 285, Issue 47, pp. 36698-708, (2010) (PubMed).
: "Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing." in: Nucleic acids research, Vol. 34, Issue 16, pp. 4622-9, (2006) (PubMed).
Synonyms and alternative names related to DGCR8
DGCR8 microprocessor complex subunit L homeolog (dgcr8.L), DiGeorge syndrome critical region gene 8 (DGCR8), DGCR8 microprocessor complex subunit (dgcr8), DGCR8, microprocessor complex subunit (DGCR8), DGCR8, microprocessor complex subunit (Dgcr8), DGCR8 microprocessor complex subunit (Dgcr8), microRNA 3618 (MIR3618), C22orf12, D16H22S788E, D16H22S1742E, D16Wis2, DGCR8, dgcrk6, DGCRK6, gy1, Gy1, MGC78846, N41, pasha, si:ch211-106a19.4, Vo59c07, wu:fc23f08, wu:fc38f06Protein level used designations for DGCR8
- hypothetical protein LOC432110
- DiGeorge syndrome critical region gene 8
- DiGeorge syndrome critical region 8
- microprocessor complex subunit DGCR8
- diGeorge syndrome critical region 8 homolog
- DiGeorge syndrome critical region 8 homolog
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