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Desmocollin 2 Products

(Desmocollin 2 (DSC2))

Categories

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured Desmocollin 2 Categories

Desmocollin 2 Antibodies

High quality antibodies with extensive validation data.

Desmocollin 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Desmocollin 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Desmocollin 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN515076
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, FACS, StM
Validations
  • (3)
Cat. No. ABIN6939250
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238891
Quantity 200 μL
Datasheet Datasheet

Recommended Desmocollin 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955364
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882654
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951114
Quantity 96 tests
Datasheet Datasheet

Recommended Desmocollin 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352016
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352018
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352020
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Desmocollin 2 products

Wu, Zhou, Duan, Wang, Xiao, Duan, Li, Li, Wan, Liu, Song, Zhou, Huang, Wang: "Reconstruction of auto-tissue-engineered lamellar cornea by dynamic culture for transplantation: a rabbit model." in: PLoS ONE, Vol. 9, Issue 4, pp. e93012, (2014) (PubMed).

Hamidov, Altendorf-Hofmann, Chen, Settmacher, Petersen, Knösel: "Reduced expression of desmocollin 2 is an independent prognostic biomarker for shorter patients survival in pancreatic ductal adenocarcinoma." in: Journal of clinical pathology, Vol. 64, Issue 11, pp. 990-4, (2012) (PubMed).

Cui, Chen, Yang, Mireskandari, Knösel, Zhang, Kohler, Kunze, Presselt, Petersen: "Diagnostic and prognostic impact of desmocollins in human lung cancer." in: Journal of clinical pathology, Vol. 65, Issue 12, pp. 1100-6, (2012) (PubMed).

Gehmlich, Syrris, Peskett, Evans, Ehler, Asimaki, Anastasakis, Tsatsopoulou, Vouliotis, Stefanadis, Saffitz, Protonotarios, McKenna: "Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations." in: Cardiovascular research, Vol. 90, Issue 1, pp. 77-87, (2011) (PubMed).

Buxton, Cowin, Franke, Garrod, Green, King, Koch, Magee, Rees, Stanley: "Nomenclature of the desmosomal cadherins." in: The Journal of cell biology, Vol. 121, Issue 3, pp. 481-3, (1993) (PubMed).

Synonyms and alternative names related to Desmocollin 2

desmocollin 2 (DSC2), desmocollin 2 (Dsc2), ARVD11, AW228162, CDHF2, DG2, DGII/III, DSC2, Dsc2a, Dsc2b, DSC3

Protein level used designations for Desmocollin 2

  • cadherin family member 2
  • desmocollin-2
  • desmosomal glycoprotein II/III
  • epithelial type 2 desmocollin
  • desmocollin type 2
  • desmocollin 2
  • desmocollin-2-like
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