Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DERL1 Products

(Der1-Like Domain Family, Member 1 (DERL1))

Categories

The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured DERL1 Categories

DERL1 Antibodies

High quality antibodies with extensive validation data.

DERL1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DERL1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN652693
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (2)
Cat. No. ABIN1386486
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p), FACS
Validations
  • (2)
Cat. No. ABIN1978394
Quantity 200 μL
Datasheet Datasheet

Recommended DERL1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351467
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351465
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our DERL1 products

Sugawara, Kano, Murata: "Rab2A is a pivotal switch protein that promotes either secretion or ER-associated degradation of (pro)insulin in insulin-secreting cells." in: Scientific reports, Vol. 4, pp. 6952, (2014) (PubMed).

Huttunen, Guénette, Peach, Greco, Xia, Kim, Barren, Tanzi, Kovacs: "HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation." in: The Journal of biological chemistry, Vol. 282, Issue 38, pp. 28285-95, (2007) (PubMed).

Schekman: "Cell biology: a channel for protein waste." in: Nature, Vol. 429, Issue 6994, pp. 817-8, (2004) (PubMed).

Synonyms and alternative names related to DERL1

Derlin-1 (Der-1), derlin-1 (EDI_023440), derlin-1.1 (PTRG_01331), hypothetical protein (derl1), Der1-like domain family, member 1 (DERL1), derlin 1 (derl1), derlin 1 L homeolog (derl1.L), derlin 1 (DERL1), Der1-like domain family, member 1 (Derl1), derlin 1 (Derl1), DERLIN-1 (DER1), 1110021N07Rik, AI195141, AW551338, CG10908, DDBDRAFT_0188135, DDBDRAFT_0266772, DDB_0188135, DDB_0266772, DER-1, DER1, Derlin-1, derlin-1, DERLIN-1, Dmel\\CG10908, F17A13.150, F17A13_150, MGC84200, RGD1311835, wu:fb09d07, wu:fb94d05, wu:fj92g12, zgc:55637

Protein level used designations for DERL1

  • CG10908-PA
  • CG10908-PB
  • Der-1-PA
  • Der-1-PB
  • Dm Derlin-1
  • derlin-1
  • derlin-1.1
  • Der1-like domain family, member 1
  • Der1-like protein 1
  • degradation in endoplasmic reticulum protein 1
  • der1-like protein 1
  • DERtrin-1
You are here:
Support