DEPTOR Products
(DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
Categories
Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes (By similarity).
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Featured DEPTOR Categories
DEPTOR Antibodies
High quality antibodies with extensive validation data.
DEPTOR ELISA Kits
Reliable ELISA kits for a wide range of species.
DEPTOR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DEPTOR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro)
Validations
- (2)
- (4)
Cat. No.
ABIN1387597
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN528709
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7266738
Quantity
100 μL
Datasheet
Datasheet
Recommended DEPTOR ELISA Kits
Recommended DEPTOR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351458
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3078983
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122407
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DEPTOR products
: "Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation." in: The Journal of nutrition, Vol. 148, Issue 6, pp. 825-833, (2019) (PubMed).: "DEPTOR inhibits cell proliferation and confers sensitivity to dopamine agonist in pituitary adenoma." in: Cancer letters, Vol. 459, pp. 135-144, (2019) (PubMed).
: "Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress." in: Nucleic acids research, Vol. 46, Issue 18, pp. 9601-9616, (2019) (PubMed).
: "Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation." in: Scientific reports, Vol. 9, Issue 1, pp. 14910, (2019) (PubMed).
: "Identification and Validation of SAA4 as a Rheumatoid Arthritis Prescreening Marker by Liquid Chromatography Tandem-mass Spectrometry." in: Molecules (Basel, Switzerland), Vol. 22, Issue 5, (2018) (PubMed).
: "Loss of hepatic DEPTOR alters the metabolic transition to fasting." in: Molecular metabolism, Vol. 6, Issue 5, pp. 447-458, (2017) (PubMed).
: "Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity." in: Molecular metabolism, Vol. 5, Issue 2, pp. 102-12, (2016) (PubMed).
: "PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639." in: Scientific reports, Vol. 6, pp. 36968, (2016) (PubMed).
: "The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway." in: Nature communications, Vol. 7, pp. 12700, (2016) (PubMed).
: "High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma." in: OncoTargets and therapy, Vol. 8, pp. 3449-55, (2015) (PubMed).
Synonyms and alternative names related to DEPTOR
DEP domain containing MTOR interacting protein (DEPTOR), DEP domain containing MTOR-interacting protein (Deptor), DEP domain containing MTOR-interacting protein (DEPTOR), 4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, DEP.6, DEPDC6, Depdc6, Depdc6-001, Depdc6-002, mKIAA4200, R75183, RAPGEF4, RGD1561030Protein level used designations for DEPTOR
- DEP domain containing MTOR-interacting protein
- DEP domain containing 6
- DEP domain containing mTOR interacting protein
- DEP domain-containing mTOR-interacting protein
- DEP domain-containing protein 6
- Rap guanine nucleotide exchange factor (GEF) 4
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