Deoxycholate Products
(Deoxycholate)
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This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].
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Recommended Deoxycholate Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Various Species
Application
CLIA, ELISA, ICC, IHC (fro)
Validations
Cat. No.
ABIN7429718
Quantity
100 μL
Datasheet
Datasheet
Recommended Deoxycholate ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6955344
Quantity
96 tests
Datasheet
Datasheet
Recommended Deoxycholate Proteins
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