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Defensin, alpha 1 Products

(Defensin, alpha 1 (DEFA1))
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, May 2010].

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Featured Defensin, alpha 1 Categories

Defensin, alpha 1 Antibodies

High quality antibodies with extensive validation data.

Defensin, alpha 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Defensin, alpha 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Defensin, alpha 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN6139522
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7433975
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7433978
Quantity 100 μL
Datasheet Datasheet

Recommended Defensin, alpha 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955300
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955301
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955302
Quantity 96 tests
Datasheet Datasheet

Recommended Defensin, alpha 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351408
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412398
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394702
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Defensin, alpha 1 products

Pero, Brancaccio, Mennitti, Gentile, Franco, Laneri, De Biasi, Pagliuca, Colicchio, Salvatore, DAlicandro, Terracciano, Cennamo, La Civita, Liotti, Mazzaccara, Frisso, Lombardo, Scudiero: "HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes." in: Antibiotics (Basel, Switzerland), Vol. 9, Issue 6, (2020) (PubMed).

Prado, Locachevic, Zoccal, Paula-Silva, Fontanari, Ferreira, Pereira, Gardinassi, Ramos, Sorgi, Darini, Faccioli: "Leukotriene B4 is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection." in: Scientific reports, Vol. 7, Issue 1, pp. 17658, (2019) (PubMed).

Fraisier, Papa, Granjeaud, Hintzen, Martina, Camoin, Almeras: "Cerebrospinal fluid biomarker candidates associated with human WNV neuroinvasive disease." in: PLoS ONE, Vol. 9, Issue 4, pp. e93637, (2014) (PubMed).

Castañeda-Delgado, Cervantes-Villagrana, Serrano-Escobedo, Frausto-Lujan, Rivas-Santiago, Enciso-Moreno, Rivas-Santiago: "Tuberculin skin test and interferon-gamma release assay values are associated with antimicrobial peptides expression in  polymorphonuclear cells during latent tuberculous infection." in: Memórias do Instituto Oswaldo Cruz, Vol. 109, Issue 3, pp. 330-4, (2014) (PubMed).

Chang, Vargas, DelPortillo, Klotman: "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." in: The Journal of clinical investigation, Vol. 115, Issue 3, pp. 765-73, (2005) (PubMed).

Synonyms and alternative names related to Defensin, alpha 1

defensin alpha 1 (DEFA1), defensin, alpha 1 (Defa1), defensin, alpha 1 (DEFA1), defensin alpha 5 (Defa5), alpha-defensin 1A (MNP1A), defensin 1 (Def1), neutrophil defensin 1 (LOC107973256), Def, DEF1, Defa, DEFA1, DEFA2, Defcr, Defcr1, GB19392, HNP-1, HP-1, HP1, MRS

Protein level used designations for Defensin, alpha 1

  • defensin, alpha 1, myeloid-related sequence
  • defensin, alpha 2
  • myeloid-related sequence
  • neutrophil defensin 1
  • alpha-defensin 1
  • cryptdin-1
  • defensin related cryptdin peptide 1
  • defensin-1
  • defensin-related cryptdin peptide
  • defensin alpha 1
  • Paneth cell-specific alpha-defensin 2
  • alpha-defensin 5, Paneth cell-specific
  • defensin NP-2
  • neutrophil antibiotic peptide NP-1
  • neutrophil antibiotic peptide NP-2
  • neutrophil defensin 2
  • ratNP-1
  • ratNP-2
  • Neutrophil defensin 1
  • Neutrophil defensin 3
  • RMAD-1
  • RMAD-3
  • RMAD-8
  • neutrophil defensin 8
  • royalisin
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